7.3.2
Natural Selection & Evolution
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Survival
Individuals must survive and reproduce to pass on their genes to their offspring. Whether an individual is capable of surviving or not is influenced by the following factors:

Predation
- Predation can decrease the probability of survival.
- If an individual is exposed to high predation, they are more likely to be eaten by a predator.
- If an individual is better at avoiding predators, they are more likely to survive and reproduce.
- The genes that allow an individual to avoid predation are more likely to be passed onto offspring.

Disease
- Disease can decrease the probability of survival.
- If an individual is better at combatting disease or avoiding infection, they are more likely to survive and reproduce.
- The genes that allow an individual to avoid disease are more likely to be passed onto offspring.

Competition
- Competition can decrease the probability of survival.
- Competition can exist between species (interspecific) or within species (intraspecific).
- If an individual is better at outcompeting other individuals, they are more likely to survive and reproduce.
- The genes that allow an individual to outcompete are more likely to be passed onto offspring.
Natural Selection and Evolution
Natural selection is the process where the frequency of alleles in a population changes over time. Natural selection is a process that gives rise to evolution.

Selective advantage
- Genetic variation exists between individuals in a population.
- Some individuals will be more likely to survive (e.g. by being better at fighting disease) than others.
- Individuals that are better at surviving than others have a selective advantage.

Producing offspring
- Individuals with a selective advantage are more likely to survive to reproduce than others.
- This means that the genes of an individual with a selective advantage are more likely to be passed onto offspring than the genes of an individual without a selective advantage.

Increasing allele frequencies
- Individuals with a selective advantage are more likely to pass on their beneficial alleles than other individuals.
- The next generation is more likely to have alleles that provide a selective advantage than alleles that do not.
- This generation is also more likely to survive to reproduce and pass on their genes.
- This causes the alleles that provide a selective advantage to increase in frequency in the population.

Natural selection
- The process where the frequency of beneficial alleles increases over time is called natural selection.
- Natural selection controls the frequency of alleles in a population.
- If a harmful allele develops in an individual, this individual is less likely to survive and the harmful allele will decrease in frequency. This is also natural selection.

Evolution
- The process of natural selection gives rise to evolution.
- Evolution is defined as a change in allele frequencies over time.
- E.g. The evolution of humans is the change in allele frequencies that has taken place over millions of years. This change has been driven by natural selection.
1Biological Molecules
1.1Monomers & Polymers
1.2Carbohydrates
1.3Lipids
1.4Proteins
1.4.1The Peptide Chain1.4.2Investigating Proteins1.4.3Primary & Secondary Protein Structure1.4.4Tertiary & Quaternary Protein Structure1.4.5Enzymes1.4.6Factors Affecting Enzyme Activity1.4.7Enzyme-Controlled Reactions1.4.8End of Topic Test - Lipids & Proteins1.4.9A-A* (AO3/4) - Enzymes1.4.10A-A* (AO3/4) - Proteins1.4.11Diagnostic Misconceptions - Enzyme Inhibitors
1.5Nucleic Acids
1.6ATP
1.7Water
1.8Inorganic Ions
2Cells
2.1Cell Structure
2.2Mitosis & Cancer
2.3Transport Across Cell Membrane
2.4Cell Recognition & the Immune System
2.4.1Immune System2.4.2Phagocytosis2.4.3T Lymphocytes2.4.4B Lymphocytes2.4.5Antibodies2.4.6Primary & Secondary Response2.4.7Vaccines2.4.8HIV2.4.9Ethical Issues2.4.10End of Topic Test - Immune System2.4.11Exam-Style Question - Immune System2.4.12A-A* (AO3/4) - Immune System2.4.13Diagnostic Misconceptions - Humoral vs Cellular
3Substance Exchange
3.1Surface Area to Volume Ratio
3.2Gas Exchange
3.3Digestion & Absorption
3.4Mass Transport
3.4.1Haemoglobin3.4.2Oxygen Transport3.4.3The Circulatory System3.4.4The Heart3.4.5Blood Vessels3.4.6Cardiovascular Disease3.4.7Heart Dissection3.4.8Xylem3.4.9Phloem3.4.10Investigating Plant Transport3.4.11End of Topic Test - Mass Transport3.4.12A-A* (AO3/4) - Mass Transport3.4.13Diagnostic Misconceptions - Concentration Gradient3.4.14Diagnostic Misconceptions - Cardiac Cycle3.4.15Diagnostic Misconceptions - Carrying Capacity3.4.16Diagnostic Misconceptions - Translocation
4Genetic Information & Variation
4.1DNA, Genes & Chromosomes
4.2DNA & Protein Synthesis
4.3Mutations & Meiosis
4.4Genetic Diversity & Adaptation
4.5Species & Taxonomy
4.6Biodiversity Within a Community
4.7Investigating Diversity
5Energy Transfers (A2 only)
5.1Photosynthesis
5.1.1Overview of Photosynthesis5.1.2Photoionisation of Chlorophyll5.1.3Production of ATP & Reduced NADP5.1.4Cyclic Photophosphorylation5.1.5Light-Independent Reaction5.1.6A-A* (AO3/4) - Photosynthesis Reactions5.1.7Limiting Factors5.1.8Photosynthesis Experiments5.1.9End of Topic Test - Photosynthesis5.1.10A-A* (AO3/4) - Photosynthesis
5.2Respiration
5.2.1Overview of Respiration5.2.2Anaerobic Respiration5.2.3A-A* (AO3/4) - Anaerobic Respiration5.2.4The Link Reaction5.2.5The Krebs Cycle5.2.6Oxidative Phosphorylation5.2.7Respiration Experiments5.2.8End of Topic Test - Respiration5.2.9A-A* (AO3/4) - Respiration5.2.10Diagnostic Misconceptions - Aerobic vs Anaerobic
5.3Energy & Ecosystems
6Responding to Change (A2 only)
6.1Nervous Communication
6.2Nervous Coordination
6.3Muscle Contraction
6.4Homeostasis
6.4.1Overview of Homeostasis6.4.2Blood Glucose Concentration6.4.3Controlling Blood Glucose Concentration6.4.4End of Topic Test - Blood Glucose6.4.5Primary & Secondary Messengers6.4.6Diabetes Mellitus6.4.7Measuring Glucose Concentration6.4.8Osmoregulation6.4.9Controlling Blood Water Potential6.4.10ADH6.4.11End of Topic Test - Diabetes & Osmoregulation6.4.12A-A* (AO3/4) - Homeostasis6.4.13Diagnostic Misconceptions - Effect of ADH
7Genetics & Ecosystems (A2 only)
7.1Genetics
7.2Populations
7.3Evolution
7.3.1Variation7.3.2Natural Selection & Evolution7.3.3End of Topic Test - Populations & Evolution7.3.4Types of Selection7.3.5Types of Selection Summary7.3.6Overview of Speciation7.3.7Causes of Speciation7.3.8Diversity7.3.9End of Topic Test - Selection & Speciation7.3.10A-A* (AO3/4) - Populations & Evolution7.3.11Diagnostic Misconceptions - Types of Speciation
8The Control of Gene Expression (A2 only)
8.1Mutation
8.2Gene Expression
8.2.1Stem Cells8.2.2Stem Cells in Disease8.2.3End of Topic Test - Mutation & Gene Epression8.2.4A-A* (AO3/4) - Mutation & Stem Cells8.2.5Regulating Transcription8.2.6Epigenetics8.2.7Epigenetics & Disease8.2.8Regulating Translation8.2.9Experimental Data8.2.10End of Topic Test - Transcription & Translation8.2.11Tumours8.2.12Correlations & Causes8.2.13Prevention & Treatment8.2.14End of Topic Test - Cancer8.2.15A-A* (AO3/4) - Gene Expression & Cancer
8.3Genome Projects
Jump to other topics
1Biological Molecules
1.1Monomers & Polymers
1.2Carbohydrates
1.3Lipids
1.4Proteins
1.4.1The Peptide Chain1.4.2Investigating Proteins1.4.3Primary & Secondary Protein Structure1.4.4Tertiary & Quaternary Protein Structure1.4.5Enzymes1.4.6Factors Affecting Enzyme Activity1.4.7Enzyme-Controlled Reactions1.4.8End of Topic Test - Lipids & Proteins1.4.9A-A* (AO3/4) - Enzymes1.4.10A-A* (AO3/4) - Proteins1.4.11Diagnostic Misconceptions - Enzyme Inhibitors
1.5Nucleic Acids
1.6ATP
1.7Water
1.8Inorganic Ions
2Cells
2.1Cell Structure
2.2Mitosis & Cancer
2.3Transport Across Cell Membrane
2.4Cell Recognition & the Immune System
2.4.1Immune System2.4.2Phagocytosis2.4.3T Lymphocytes2.4.4B Lymphocytes2.4.5Antibodies2.4.6Primary & Secondary Response2.4.7Vaccines2.4.8HIV2.4.9Ethical Issues2.4.10End of Topic Test - Immune System2.4.11Exam-Style Question - Immune System2.4.12A-A* (AO3/4) - Immune System2.4.13Diagnostic Misconceptions - Humoral vs Cellular
3Substance Exchange
3.1Surface Area to Volume Ratio
3.2Gas Exchange
3.3Digestion & Absorption
3.4Mass Transport
3.4.1Haemoglobin3.4.2Oxygen Transport3.4.3The Circulatory System3.4.4The Heart3.4.5Blood Vessels3.4.6Cardiovascular Disease3.4.7Heart Dissection3.4.8Xylem3.4.9Phloem3.4.10Investigating Plant Transport3.4.11End of Topic Test - Mass Transport3.4.12A-A* (AO3/4) - Mass Transport3.4.13Diagnostic Misconceptions - Concentration Gradient3.4.14Diagnostic Misconceptions - Cardiac Cycle3.4.15Diagnostic Misconceptions - Carrying Capacity3.4.16Diagnostic Misconceptions - Translocation
4Genetic Information & Variation
4.1DNA, Genes & Chromosomes
4.2DNA & Protein Synthesis
4.3Mutations & Meiosis
4.4Genetic Diversity & Adaptation
4.5Species & Taxonomy
4.6Biodiversity Within a Community
4.7Investigating Diversity
5Energy Transfers (A2 only)
5.1Photosynthesis
5.1.1Overview of Photosynthesis5.1.2Photoionisation of Chlorophyll5.1.3Production of ATP & Reduced NADP5.1.4Cyclic Photophosphorylation5.1.5Light-Independent Reaction5.1.6A-A* (AO3/4) - Photosynthesis Reactions5.1.7Limiting Factors5.1.8Photosynthesis Experiments5.1.9End of Topic Test - Photosynthesis5.1.10A-A* (AO3/4) - Photosynthesis
5.2Respiration
5.2.1Overview of Respiration5.2.2Anaerobic Respiration5.2.3A-A* (AO3/4) - Anaerobic Respiration5.2.4The Link Reaction5.2.5The Krebs Cycle5.2.6Oxidative Phosphorylation5.2.7Respiration Experiments5.2.8End of Topic Test - Respiration5.2.9A-A* (AO3/4) - Respiration5.2.10Diagnostic Misconceptions - Aerobic vs Anaerobic
5.3Energy & Ecosystems
6Responding to Change (A2 only)
6.1Nervous Communication
6.2Nervous Coordination
6.3Muscle Contraction
6.4Homeostasis
6.4.1Overview of Homeostasis6.4.2Blood Glucose Concentration6.4.3Controlling Blood Glucose Concentration6.4.4End of Topic Test - Blood Glucose6.4.5Primary & Secondary Messengers6.4.6Diabetes Mellitus6.4.7Measuring Glucose Concentration6.4.8Osmoregulation6.4.9Controlling Blood Water Potential6.4.10ADH6.4.11End of Topic Test - Diabetes & Osmoregulation6.4.12A-A* (AO3/4) - Homeostasis6.4.13Diagnostic Misconceptions - Effect of ADH
7Genetics & Ecosystems (A2 only)
7.1Genetics
7.2Populations
7.3Evolution
7.3.1Variation7.3.2Natural Selection & Evolution7.3.3End of Topic Test - Populations & Evolution7.3.4Types of Selection7.3.5Types of Selection Summary7.3.6Overview of Speciation7.3.7Causes of Speciation7.3.8Diversity7.3.9End of Topic Test - Selection & Speciation7.3.10A-A* (AO3/4) - Populations & Evolution7.3.11Diagnostic Misconceptions - Types of Speciation
8The Control of Gene Expression (A2 only)
8.1Mutation
8.2Gene Expression
8.2.1Stem Cells8.2.2Stem Cells in Disease8.2.3End of Topic Test - Mutation & Gene Epression8.2.4A-A* (AO3/4) - Mutation & Stem Cells8.2.5Regulating Transcription8.2.6Epigenetics8.2.7Epigenetics & Disease8.2.8Regulating Translation8.2.9Experimental Data8.2.10End of Topic Test - Transcription & Translation8.2.11Tumours8.2.12Correlations & Causes8.2.13Prevention & Treatment8.2.14End of Topic Test - Cancer8.2.15A-A* (AO3/4) - Gene Expression & Cancer
8.3Genome Projects
Practice questions on Natural Selection & Evolution
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