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Co-Transporters

After the larger molecules have been hydrolysed into monomers, they must be absorbed by the cells. Amino acids and monosaccharides are absorbed through epithelial cells. This involves co-transporters.

Active transport of sodium ions

Active transport of sodium ions

  • Sodium-dependent co-transporter proteins are located in the epithelial cell membranes.
  • The co-transporter proteins actively transport sodium ions into the blood.
  • This causes the concentration of sodium ions in the epithelial cells to decrease.
Diagram
Diffusion of sodium ions

Diffusion of sodium ions

  • The decreased concentration of sodium ions in the epithelial cells causes sodium ions in the ileum to diffuse down their concentration gradient.
  • The sodium ions diffuse through a co-transporter protein in the cell surface membrane.
Binding of amino acids & sugars

Binding of amino acids & sugars

  • When sodium ions bind to a co-transporter protein, amino acids or monosaccharides also bind to the protein.
  • Binding of amino acids or monosaccharides causes the transporter protein to undergo a conformational change.
  • The amino acids or monosaccharides, along with the sodium ions are transported into the epithelial cell cytoplasm.
Diagram
Use

Use

  • Once inside the epithelial cells, the amino acids or monosaccharides can then be used inside the epithelial cells or absorbed into the bloodstream.

Micelles

Lipids are absorbed from the ileum through epithelial cells. This involves the formation of micelles.

Formation

Formation

  • After larger, lipid molecules have been broken down into monoglycerides and fatty acids, bile salts are secreted by the liver.
  • The bile salts associate with the monoglycerides and fatty acids to form micelles.
  • Micelles are circular formations that are made up of phospholipid tails.
Incorporation

Incorporation

  • The micelles move through the ileum and come into contact with the epithelial cells.
  • The micelles incorporate themselves into the epithelial cell surface membrane and are absorbed.
Jump to other topics
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Biological Molecules

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Cells

3

Substance Exchange

4

Genetic Information & Variation

5

Energy Transfers (A2 only)

6

Responding to Change (A2 only)

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The Control of Gene Expression (A2 only)

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Mathematical Skills

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