3.3.2
Digestion in Mammals
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Carbohydrates
Carbohydrates are a staple in the mammalian diet. The digestion of carbohydrates begins in the mouth and involves the enzyme amylase.

Amylase
- Amylase is an enzyme that is produced in the salivary glands and the pancreas.
- Amylase catalyses the hydrolysis of starch (carbohydrate) into maltose (disaccharide).
- Hydrolysis of carbohydrates breaks bonds called glycosidic bonds.
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Membrane-bound disaccharidases
- Membrane-bound disaccharidases are enzymes in the cell membranes of the epithelial cells in the ileum (the small intestine).
- Membrane-bound disaccharidases catalyse the hydrolysation of disaccharides (e.g. maltose) into monosaccharides (e.g. glucose).

Transporter proteins
- Monosaccharides are transported into the epithelial cells in the ileum using transporter proteins.
- Glucose and galactose are transported by co-transporter proteins.
- Fructose is absorbed by facilitated diffusion.
- Once inside the cells, monosaccharides can be used in respiration.
Lipids
Lipids are a staple in the mammalian diet. Most of the digestion of lipids takes place in the small intestine and involves the enzyme lipase.

Lipase
- Lipase is an enzyme that is produced by the pancreas and is released into the small intestine.
- Lipase hydrolyses lipids into fatty acids and monoglycerides.
- Hydrolysis of lipids breaks bonds called ester bonds.

Bile salts
- Bile salts are produced by the liver.
- Bile salts also help digest lipids by forming small lipid droplets called micelles.
- The process of forming micelles is called emulsification.
- The many micelles have a larger surface area than a single larger micelle. This allows the lipids to be hydrolysed by lipase more quickly.

Micelles
- The micelles allow the monoglycerides and fatty acids to be absorbed by the epithelial cells in the ileum.
- The monoglycerides and fatty acids diffuse through the cell surface membrane into the cell cytoplasm.
Proteins
Proteins are a staple in the mammalian diet. Most of the digestion of proteins takes place in the small intestine and involves different enzymes called proteases. Some digestion occurs in the stomach.

Endopeptidases
- Endopeptidases are enzymes that catalyse the hydrolysis of bonds within a protein to amino acids.
- Hydrolysis of proteins breaks bonds called peptide bonds.
- Examples of endopeptidases include trypsin, chymotrypsin and pepsin.
- Trypsin and chymotrypsin are released by the pancreas into the small intestine.
- Pepsin is released into the stomach.

Exopeptidases
- Exopeptidases are enzymes that catalyse the hydrolysis of peptide bonds at the ends of proteins.
- E.g. Dipeptidases hydrolyse the peptide bond between two amino acids.

Co-transporter proteins
- Amino acids are transported into the epithelial cells in the ileum using co-transporter proteins.
1Biological Molecules
1.1Monomers & Polymers
1.2Carbohydrates
1.3Lipids
1.4Proteins
1.5Nucleic Acids
1.6ATP
1.7Water
1.8Inorganic Ions
2Cells
2.1Cell Structure
2.2Mitosis & Cancer
2.3Transport Across Cell Membrane
2.4Cell Recognition & the Immune System
3Substance Exchange
3.1Surface Area to Volume Ratio
3.2Gas Exchange
3.3Digestion & Absorption
3.4Mass Transport
4Genetic Information & Variation
4.1DNA, Genes & Chromosomes
4.2DNA & Protein Synthesis
4.3Mutations & Meiosis
4.4Genetic Diversity & Adaptation
4.5Species & Taxonomy
4.6Biodiversity Within a Community
4.7Investigating Diversity
5Energy Transfers (A2 only)
5.1Photosynthesis
5.2Respiration
5.3Energy & Ecosystems
6Responding to Change (A2 only)
6.1Nervous Communication
6.2Nervous Coordination
6.3Muscle Contraction
6.4Homeostasis
7Genetics & Ecosystems (A2 only)
7.1Genetics
7.2Populations
7.3Evolution
8The Control of Gene Expression (A2 only)
8.1Mutation
8.2Gene Expression
8.3Genome Projects
Jump to other topics
1Biological Molecules
1.1Monomers & Polymers
1.2Carbohydrates
1.3Lipids
1.4Proteins
1.5Nucleic Acids
1.6ATP
1.7Water
1.8Inorganic Ions
2Cells
2.1Cell Structure
2.2Mitosis & Cancer
2.3Transport Across Cell Membrane
2.4Cell Recognition & the Immune System
3Substance Exchange
3.1Surface Area to Volume Ratio
3.2Gas Exchange
3.3Digestion & Absorption
3.4Mass Transport
4Genetic Information & Variation
4.1DNA, Genes & Chromosomes
4.2DNA & Protein Synthesis
4.3Mutations & Meiosis
4.4Genetic Diversity & Adaptation
4.5Species & Taxonomy
4.6Biodiversity Within a Community
4.7Investigating Diversity
5Energy Transfers (A2 only)
5.1Photosynthesis
5.2Respiration
5.3Energy & Ecosystems
6Responding to Change (A2 only)
6.1Nervous Communication
6.2Nervous Coordination
6.3Muscle Contraction
6.4Homeostasis
7Genetics & Ecosystems (A2 only)
7.1Genetics
7.2Populations
7.3Evolution
8The Control of Gene Expression (A2 only)
8.1Mutation
8.2Gene Expression
8.3Genome Projects
Practice questions on Digestion in Mammals
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- 1
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- 3Steps in Digestion of CarbohydratesPut in order
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- 5What are the stages of digestion of lipids?Fill in the list
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