Physiology of Stress

The Stress Response

Stress is a response to a threatening stimulus that we perceive is greater than the resources we have to deal with it. These resources may be within the environment or related to our own abilities.

Own judgement

A key thing to remember is that the stress response is triggered by a judgement which we make and we often incorrectly estimate the demands of a situation.
Regardless of whether we actually have the resources to cope with a situation or not, if we perceive we cannot, then the stress response will be induced.

Brain regions

Judgements about whether a stimulus is a stressor or not, are made in the cerebral cortex.
If a stimulus is judged to be a stressor, the cerebral cortex sends signals to the hypothlamus which triggers the stress response.

Sympathomedullary pathway

First described by Cannon (1932) as the ‘fight or flight’ response, this is the first stage of the stress response.
The sympathetic branch of the autonomic nervous system is activated. This causes the adrenal medulla (the central part of the adrenal gland) to release adrenaline and noradrenaline into the blood.

Effects of sympathetic arousal

The arousal of the sympathetic nervous system causes physiological changes that help the body prepare to deal with threat and prepare to either fight or flee. These changes are:
- Pupils dilate.
- Heart and breathing rate increase.
- Blood is diverted from digestion in the stomach to the muscles in the legs and arms.

HPA system

If the stress persists over a long period of time, the Hypothalamic Pituitary-Adrenal (HPA) System is activated.
As the sympathomedullary pathway is very intense, it uses a lot of bodily resources. So the HPA system works to support this by producing more fuel for the body.

General adaptation syndrome

Hans Selye first proposed the general adaptation syndrome in the 1930s. The general adaptation syndrome describes the body’s nonspecific physiological response to stress - that regardless of the type of stressor, the same pattern of reactions happens.

Hypothalamic Pituitary-Adrenal System and Stress

The HPA System is activated with the sympathomedullary pathway and produces fuel to support the ‘fight or flight’ response. But extended activation of this system has negative effects on the body.

Mechanism of the HPA

In response to stress, the hypothalamus releases corticotrophin-releasing hormone (CRH).
This stimulates the anterior pituitary gland to release adrenocorticotropic hormone (ACTH).
ACTH then activates the adrenal cortex (the outer part of the adrenal glands) to secrete a number of hormones into the bloodstream, including cortisol.

Cortisol

Cortisol is commonly known as the stress hormone, and helps provide that boost of energy when we first encounter a stressor, preparing us to run away or fight.
Cortisol converts protein to glucose, which provides this extra energy.
Cortisol also improves immune system functioning temporarily and decreases pain sensitivity.
In short bursts, this process is very beneficial.

Negative effects of cortisol

Prolonged, chronic stress leads to prolonged HPA system activation and so extended release of cortisol.
High levels of cortisol have been shown to produce a number of harmful effects, including weakening of the immune system.
High levels of cortisol have been regularly observed in individuals with psychological disorders such as depression.

Evolution

In the early years of humanity, most stressors would have been physical threats. So the physiological stress response would have been beneficial for survival.
But in today’s society, most stressors are psychological and long term. So the physiological stress response is often activated to no real gain, and may be doing us more harm than good.

The General Adaptation Syndrome and Stress

Hans Selye proposed the general adaption syndrome in the 1930s. The general adaptation syndrome is the body’s nonspecific physiological response to stress - regardless of the type of stressor, the same pattern of reactions happens.

Selye's observations

In the 1930s, Selye was researching sex hormones in rats.
Selye observed that rats became ill when exposed to prolonged negative stimulation (stressors) such as extreme cold, surgical injury, excessive muscular exercise and shock.
Selye referred to this as the general adaptations syndrome and proposed that there were three distinct steps.

Stage 1 - alarm reaction

The alarm reaction describes the body’s immediate reaction upon facing a threatening situation or emergency. It is roughly analogous to the fight-or-flight response that Cannon described.
During an alarm reaction, you are alerted to a stressor and your body alarms you with a cascade of physiological reactions that provide you with the energy to manage the situation.

Stage 2 - stage of resistance

If exposure to a stressor is prolonged, the organism will enter the stage of resistance.
During this stage, the initial shock of the alarm reaction has worn off and the body has adapted to the stressor.
Nevertheless, the body also remains on alert and is prepared to respond as it did during the alarm reaction, although with less intensity.

Stage 3 - stage of exhaustion

If exposure to a stressor continues over a longer period of time, the stage of exhaustion comes on.
At this stage, the person is no longer able to adapt to the stressor. The body’s ability to resist becomes depleted as physical wear takes its toll on the body’s tissues and organs.
Illness, disease and other permanent damage to the body - even death - may happen as a result.

Physical focus

You should be aware that this model is a response-based conceptualisation of stress that focuses exclusively on the body’s physical responses, while largely ignoring psychological factors, such as appraisal and interpretation of threats.
The model offers a general explanation for how stress can lead to physical damage and disease, but it's likely that there are psychological mediators at play too.

1Social Influence

1.1Social Influence

1.1.1Conformity

1.1.2Asch (1951)

1.1.3Sherif (1935)

1.1.4Conformity to Social Roles

1.1.5BBC Prison Study

1.1.6End of Topic Test - Conformity

1.1.7Obedience

1.1.8Analysing Milgram's Experiment

1.1.9Agentic State & Legitimate Authority

1.1.10Variables of Obedience

1.1.11Resistance to Social Influence

1.1.12Minority Influence & Social Change

1.1.13Minority Influence & Social Impact Theory

1.1.14End of Topic Test - Social Influences

1.1.15Exam-Style Question - Conformity

1.1.16Top Grade AO2/AO3 - Social Influence

2Memory

3Attachment

3.1Attachment

3.1.1Caregiver-Infant Interaction

3.1.2Condon & Sander (1974)

3.1.3Schaffer & Emerson (1964)

3.1.4Multiple Attachments

3.1.5Studies on the Role of the Father

3.1.6Animal Studies of Attachment

3.1.7Explanations of Attachment

3.1.8Attachment Types - Strange Situation

3.1.9Cultural Differences in Attachment

3.1.10Disruption of Attachment

3.1.11Disruption of Attachment - Privation

3.1.12Overcoming the Effects of Disruption

3.1.13The Effects of Institutionalisation

3.1.14Early Attachment

3.1.15Critical Period of Attachment

3.1.16End of Topic Test - Attachment

3.1.17Exam-Style Question - Attachment

3.1.18Top Grade AO2/AO3 - Attachment

4Psychopathology

4.1Psychopathology

4.1.1Definitions of Abnormality

4.1.2Definitions of Abnormality 2

4.1.3Phobias, Depression & OCD

4.1.4Phobias: Behavioural Approach

4.1.5Evaluation of Behavioural Explanations of Phobias

4.1.6Depression: Cognitive Approach

4.1.7OCD: Biological Approach

4.1.8Evidence for the Biological Approach

4.1.9End of Topic Test - Psychopathy

4.1.10Exam-Style Question - Phobias

4.1.11Top Grade AO2/AO3 - Psychopathology

5Approaches in Psychology

5.1Approaches in Psychology

5.2Comparison of Approaches (A2 only)

5.2.1Psychodynamic Approach

5.2.2Cognitive Approach

5.2.3Biological Approach

5.2.4Behavioural Approach

5.2.5End of Topic Test - Comparison of Approaches

6Biopsychology

6.1Biopsychology

6.1.1Nervous System Divisions

6.1.2Neuron Structure & Function

6.1.3Neurotransmitters

6.1.4Endocrine System Function

6.1.5Fight or Flight Response

6.1.6The Brain (A2 only)

6.1.7Localisation of Brain Function (A2 only)

6.1.8Studying the Brain (A2 only)

6.1.9CIMT (A2 Only) & Postmortem Examinations

6.1.10Biological Rhythms (A2 only)

6.1.11Studies on Biological Rhythms (A2 Only)

6.1.12End of Topic Test - Biopsychology

6.1.13Top Grade AO2/AO3 - Biopsychology

7Research Methods

7.1Research Methods

7.1.1Experimental Method

7.1.2Observational Techniques

7.1.3Covert, Overt & Controlled Observation

7.1.4Self-Report Techniques

7.1.5Correlations

7.1.6Exam-Style Question - Research Methods

7.1.7End of Topic Test - Research Methods

7.2Scientific Processes

7.2.1Aims, Hypotheses & Sampling

7.2.2Pilot Studies & Design

7.2.3Questionnaires

7.2.4Variables & Control

7.2.5Demand Characteristics & Investigator Effects

7.2.6Ethics

7.2.7Limitations of Ethical Guidelines

7.2.8Consent & Protection from Harm Studies

7.2.9Peer Review & The Economy

7.2.10Validity (A2 only)

7.2.11Reliability (A2 only)

7.2.12Features of Science (A2 only)

7.2.13Paradigms & Falsifiability (A2 only)

7.2.14Scientific Report (A2 only)

7.2.15Scientific Report 2 (A2 only)

7.2.16End of Topic Test - Scientific Processes

7.3Data Handling & Analysis

7.3.1Types of Data

7.3.2Descriptive Statistics

7.3.3Correlation

7.3.4Evaluation of Descriptive Statistics

7.3.5Presentation & Display of Data

7.3.6Levels of Measurement (A2 only)

7.3.7Content Analysis (A2 only)

7.3.8Case Studies (A2 only)

7.3.9Thematic Analysis (A2 only)

7.3.10End of Topic Test - Data Handling & Analysis

7.4Inferential Testing

7.4.1Introduction to Inferential Testing

7.4.2Sign Test

7.4.3Piaget Conservation Experiment

7.4.4Non-Parametric Tests

8Issues & Debates in Psychology (A2 only)

8.1Issues & Debates in Psychology (A2 only)

8.1.1Culture Bias

8.1.2Sub-Culture Bias

8.1.3Gender Bias

8.1.4Ethnocentrism

8.1.5Cross Cultural Research

8.1.6Free Will & Determinism

8.1.7Comparison of Free Will & Determinism

8.1.8Reductionism & Holism

8.1.9Reductionist & Holistic Approaches

8.1.10Nature-Nurture Debate

8.1.11Interactionist Approach

8.1.12Nature-Nurture Methods

8.1.13Nature-Nurture Approaches

8.1.14Idiographic & Nomothetic Approaches

8.1.15Socially Sensitive Research

8.1.16End of Topic Test - Issues and Debates

9Option 1: Relationships (A2 only)

9.1Relationships: Sexual Relationships (A2 only)

9.1.1Sexual Selection & Human Reproductive Behaviour

9.1.2Intersexual & Intrasexual Selection

9.1.3Evaluation of Sexual Selection Behaviour

9.1.4Factors Affecting Attraction: Self-Disclosure

9.1.5Evaluation of Self-Disclosure Theory

9.1.6Self Disclosure in Computer Communication

9.1.7Factors Affecting Attraction: Physical Attributes

9.1.8Matching Hypothesis Studies

9.1.9Factors Affecting Physical Attraction

9.1.10Factors Affecting Attraction: Filter Theory 1

9.1.11Factors Affecting Attraction: Filter Theory 2

9.1.12Evaluation of Filter Theory

9.1.13End of Topic Test - Sexual Relationships

9.2Relationships: Romantic Relationships (A2 only)

9.2.1Social Exchange Theory

9.2.2Evaluation of Social Exchange Theory

9.2.3Equity Theory

9.2.4Evaluation of Equity Theory

9.2.5Rusbult’s Investment Model

9.2.6Evaluation of Rusbult's Investment Model

9.2.7Relationship Breakdown

9.2.8Studies on Relationship Breakdown

9.2.9Evaluation of Relationship Breakdown

9.2.10End of Topic Test - Romantic relationships

9.3Relationships: Virtual & Parasocial (A2 only)

9.3.1Virtual Relationships in Social Media

9.3.2Evaluation of Reduced Cues & Hyperpersonal

9.3.3Parasocial Relationships

9.3.4Attachment Theory & Parasocial Relationships

9.3.5Evaluation of Parasocial Relationship Theories

9.3.6End of Topic Test - Virtual & Parasocial Realtions

10Option 1: Gender (A2 only)

10.1Gender (A2 only)

10.1.1Sex, Gender & Androgyny

10.1.2Gender Identity Disorder

10.1.3Biological & Social Explanations of GID

10.1.4Biological Influences on Gender

10.1.5Effects of Hormones on Gender

10.1.6End of Topic Test - Gender 1

10.1.7Kohlberg’s Theory of Gender Constancy

10.1.8Evaluation of Kohlberg's Theory

10.1.9Gender Schema Theory

10.1.10Psychodynamic Approach to Gender Development 1

10.1.11Psychodynamic Approach to Gender Development 2

10.1.12Social Approach to Gender Development

10.1.13Criticisms of Social Theory

10.1.14End of Topic Test - Gender 2

10.1.15Media Influence on Gender Development

10.1.16Cross Cultural Research

10.1.17Childcare & Gender Roles

10.1.18End of Topic Test - Gender 3

11Option 1: Cognition & Development (A2 only)

11.1Cognition & Development (A2 only)

11.1.1Piaget’s Theory of Cognitive Development 1

11.1.2Piaget's Theory of Cognitive Development 2

11.1.3Schema Accommodation Assimilation & Equilibration

11.1.4Piaget & Inhelder’s Three Mountains Task (1956)

11.1.5Conservation & Class Inclusion

11.1.6Evaluation of Piaget

11.1.7End of Topic Test - Cognition & Development 1

11.1.8Vygotsky

11.1.9Evaluation of Vygotsky

11.1.10Baillargeon

11.1.11Baillargeon's studies

11.1.12Evaluation of Baillargeon

11.1.13End of Topic Test - Cognition & Development 2

11.1.14Sense of Self & Theory of Mind

11.1.15Baron-Cohen Studies

11.1.16Selman’s Five Levels of Perspective Taking

11.1.17Biological Basis of Social Cognition

11.1.18Evaluation of Biological Basis of Social Cognition

11.1.19Important Issues in Social Neuroscience

11.1.20End of Topic Test - Cognition & Development 3

11.1.21Top Grade AO2/AO3 - Cognition & Development

12Option 2: Schizophrenia (A2 only)

12.1Schizophrenia: Diagnosis (A2 only)

12.1.1Classification & Diagnosis

12.1.2Reliability & Validity of Diagnosis

12.1.3Gender & Cultural Bias

12.1.4Pinto (2017) & Copeland (1971)

12.1.5End of Topic Test - Scizophrenia Diagnosis

12.2Schizophrenia: Treatment (A2 only)

12.2.1Family-Based Psychological Explanations

12.2.2Evaluation of Family-Based Explanations

12.2.3Cognitive Explanations

12.2.4Drug Therapies

12.2.5Evaluation of Drug Therapies

12.2.6Biological Explanations for Schizophrenia

12.2.7Dopamine Hypothesis

12.2.8End of Topic Test - Schizoprenia Treatment 1

12.2.9Psychological Therapies 1

12.2.10Psychological Therapies 2

12.2.11Evaluation of Psychological Therapies

12.2.12Interactionist Approach - Diathesis-Stress Model

12.2.13Interactionist Approach - Triggers & Treatment

12.2.14Evaluation of the Interactionist Approach

12.2.15End of Topic Test - Scizophrenia Treatments 2

13Option 2: Eating Behaviour (A2 only)

13.1Eating Behaviour (A2 only)

13.1.1Explanations for Food Preferences

13.1.2Birch et al (1987) & Lowe et al (2004)

13.1.3Control of Eating Behaviours

13.1.4Control of Eating Behaviour: Leptin

13.1.5Biological Explanations for Anorexia Nervosa

13.1.6Psychological Explanations: Family Systems Theory

13.1.7Psychological Explanations: Social Learning Theory

13.1.8Psychological Explanations: Cognitive Theory

13.1.9Biological Explanations for Obesity

13.1.10Biological Explanations: Studies

13.1.11Psychological Explanations for Obesity

13.1.12Psychological Explanations: Studies

13.1.13End of Topic Test - Eating Behaviour

14Option 2: Stress (A2 only)

14.1Stress (A2 only)

14.1.1Physiology of Stress

14.1.2Role of Stress in Illness

14.1.3Role of Stress in Illness: Studies

14.1.4Social Readjustment Rating Scales

14.1.5Hassles & Uplifts Scales

14.1.6Stress, Workload & Control

14.1.7Stress Level Studies

14.1.8End of Topic Test - Stress 1

14.1.9Physiological Measures of Stress

14.1.10Individual Differences

14.1.11Stress & Gender

14.1.12Drug Therapy & Biofeedback for Stress

14.1.13Stress Inoculation Therapy

14.1.14Social Support & Stress

14.1.15End of Topic Test - Stress 2

15Option 3: Aggression (A2 only)

15.1Aggression: Physiological (A2 only)

15.1.1Neural Mechanisms

15.1.2Serotonin

15.1.3Hormonal Mechanisms

15.1.4Genetic Factors

15.1.5Genetic Factors 2

15.1.6End of Topic Test - Aggression: Physiological 1

15.1.7Ethological Explanation

15.1.8Innate Releasing Mechanisms & Fixed Action Pattern

15.1.9Evolutionary Explanations

15.1.10Buss et al (1992) - Sex Differences in Jealousy

15.1.11Evaluation of Evolutionary Explanations

15.1.12End of Topic Test - Aggression: Physiological 2

15.2Aggression: Social Psychological (A2 only)

15.2.1Social Psychological Explanation

15.2.2Buss (1963) - Frustration/Aggression

15.2.3Social Psychological Explanation 2

15.2.4Social Learning Theory (SLT) 1

15.2.5Social Learning Theory (SLT) 2

15.2.6Limitations of Social Learning Theory (SLT)

15.2.7Deindividuation

15.2.8Deindividuation 2

15.2.9Deindividuation - Diener et al (1976)

15.2.10End of Topic Test - Aggression: Social Psychology

15.2.11Institutional Aggression: Prisons

15.2.12Evaluation of Dispositional & Situational

15.2.13Influence of Computer Games

15.2.14Influence of Television

15.2.15Evaluation of Studies on Media

15.2.16Desensitisation & Disinhibition

15.2.17Cognitive Priming

15.2.18End of Topic Test - Aggression: Social Psychology

16Option 3: Forensic Psychology (A2 only)

17Option 3: Addiction (A2 only)

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