Sickle Cell & Malaria

Biology: Cambridge International GCSE Supplement, topic 18.1.5

Sickle Cell Anaemia and Malaria

There is an interesting relationship between sickle cell anaemia and malaria.

Malaria resistance

Malaria resistance

  • Individuals who are heterozygous for the sickle cell allele have increased resistance to malaria.
Is this common anywhere in particular?

Is this common anywhere in particular?

  • This is advantageous for survival in places where malaria is common.
  • It is found more frequently in African, Caribbean, Asian, Middle Eastern and Eastern Mediterranean populations for this reason.

Test yourself on Sickle Cell & Malaria

  • Individuals who are heterozygous for the sickle cell allele have increased resistance to what disease?

  • In which of these places is heterozygosity for the sickle cell allele more common?

  • What does heterozygosity for the sickle cell allele mean in the context of malaria?

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