1.2.2
RNA
Structure of RNA
Structure of RNA
RNA is usually single-stranded and is made of ribonucleotides that are linked by phosphodiester bonds.


RNA
RNA
- A ribonucleotide in the RNA chain contains ribose (the pentose sugar), one of the four nitrogenous bases (A, U, G, and C), and the phosphate group.
- Uracil (U) is a nucleotide only found in RNA. It replaces thymine and pairs with adenine.
- Uracil is a pyrimidine nucleotide.
- RNA base sequences are complementary to the DNA's coding sequence from which it has been copied.
- If the DNA strand has a sequence AATTGCGC, the sequence of the complementary RNA is UUAACGCG.




Uracil
Uracil
- Uracil is a pyrimidine nucleotide found only in RNA. It takes the place of the DNA nucleotide thymine.
- The RNA base sequence is complementary to the DNA's coding sequence from which it has been copied.
- If the DNA strand has a sequence AATTGCGC, the sequence of the complementary RNA is UUAACGCG.


Types of RNA
Types of RNA
- Ribonucleic acid, or RNA, is mainly involved in the process of protein synthesis under the direction of DNA.
- RNA is usually single-stranded and is made of ribonucleotides that are linked by phosphodiester bonds.
- There are four major types of RNA: messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and microRNA (miRNA).


mRNA
mRNA
- Messenger RNA (mRNA) carries messages from DNA, which controls all of the cellular activities in a cell.
- The sequence of nucleotides in mRNA encodes biological information.
- The RNA base sequence is complementary to the coding sequence of the DNA from which it has been copied.
- However, in RNA, the base T is absent and U is present instead.
- The mRNA is read in sets of three bases known as codons.
- Each codon codes for a single amino acid. In this way, the mRNA is read and the protein product is made.


tRNA
tRNA
- Transfer RNA (tRNA) is one of the smallest of the four types of RNA, usually 70–90 nucleotides long.
- It carries the correct amino acid to the site of protein synthesis.
- It is the base pairing between the tRNA and mRNA that allows for the correct amino acid to be inserted in the polypeptide chain.
- It has an anticodon, which is complementary to the mRNA codon.


rRNA & miRNA
rRNA & miRNA
- Ribosomal RNA (rRNA) is a major constituent of ribosomes on which the mRNA binds.
- The rRNA ensures the proper alignment of the mRNA and the ribosomes; the rRNA of the ribosome also has an enzymatic activity (peptidyl transferase) and catalyzes the formation of the peptide bonds between two aligned amino acids.
- MicroRNAs (miRNAs) are the smallest RNA molecules and their role involves the regulation of gene expression by interfering with the expression of certain mRNA messages
1Unity & Diversity - Molecules
1.1Water
1.2DNA Structure & Replication
1.3Transcription & Gene Expression
2Unity & Diversity - Cells
2.1The Origin of Cells
2.2Introduction to Cells
2.3Ultrastructure of Cells
2.4Cell Division
2.5Structure of DNA & RNA
2.6DNA Replication, Transcription & Translation
2.7Cell Respiration
2.8Photosynthesis
2.9Viruses
3Unity & Diversity - Organisms
3.1Diversity of Organisms
3.2Evidence for Evolution
4Unity & Diversity - Ecosystems
4.1Classification
4.3Evolution & Speciation
4.3.1Evidence for Evolution - Fossils & DNA
4.3.2Evidence for Evolution - Anatomy & Geography
4.3.3IB Multiple Choice - Evidence for Evolution
4.3.4Extended Response - DNA & Evolution
4.3.5Populations
4.3.6Mutations, Genetic Drift, & Gene Flow
4.3.7Speciation
4.3.8Rate of Speciation
4.3.9Allopatric & Sympatric Speciation
4.4Conservation of Biodiversity
5Form & Function - Molecules
6Form & Function - Cells
6.1Membranes & Membrane Transport
6.2Organelles & Compartmentalization
6.3Cell Specialization
7Form & Function - Organisms
7.2Transport
7.3Muscle & Motility
8Form & Function - Ecosystems
8.1Species, Communities & Ecosytems
8.3Carbon Cycle
9Interaction & Interdependence - Molecules
9.1Enzymes
9.2Metabolism
9.3Cell Respiration
10Interaction & Interdependence - Cells
10.1Chemical Signalling
10.2Neural Signalling
10.3Adaptation to Environment
10.4Ecological Niches
11Interaction & Interdependence - Organisms
11.1Integration of Body Systems
12Interaction & Interdependence - Ecosystems
12.1Populations & Communities
12.2Transfers of Energy & Matter
13Continuity & Change - Molecules
13.1DNA Replication
13.2Protein Synthesis
14Continuity & Change - Cells
15Continuity & Change - Organisms
15.1Inheritance
15.1.1Non-Nuclear Inheritance
15.1.2Linked Genes
15.1.3IB Multiple Choice - Non-Mendelian Genetics
15.1.4Extended Response - Inheritance
15.1.5Introduction to Non-Mendelian Inheritance
15.1.6Chi-Squared Test
15.1.7End of Topic Quiz - Inheritance
15.1.8Sex-Linked Genes
15.1.9Grade 4-5 (Scientific Practices) - Inheritance
16Continuity & Change - Ecosystems
16.1Natural Selection
16.2Stability & Change
Jump to other topics
1Unity & Diversity - Molecules
1.1Water
1.2DNA Structure & Replication
1.3Transcription & Gene Expression
2Unity & Diversity - Cells
2.1The Origin of Cells
2.2Introduction to Cells
2.3Ultrastructure of Cells
2.4Cell Division
2.5Structure of DNA & RNA
2.6DNA Replication, Transcription & Translation
2.7Cell Respiration
2.8Photosynthesis
2.9Viruses
3Unity & Diversity - Organisms
3.1Diversity of Organisms
3.2Evidence for Evolution
4Unity & Diversity - Ecosystems
4.1Classification
4.3Evolution & Speciation
4.3.1Evidence for Evolution - Fossils & DNA
4.3.2Evidence for Evolution - Anatomy & Geography
4.3.3IB Multiple Choice - Evidence for Evolution
4.3.4Extended Response - DNA & Evolution
4.3.5Populations
4.3.6Mutations, Genetic Drift, & Gene Flow
4.3.7Speciation
4.3.8Rate of Speciation
4.3.9Allopatric & Sympatric Speciation
4.4Conservation of Biodiversity
5Form & Function - Molecules
6Form & Function - Cells
6.1Membranes & Membrane Transport
6.2Organelles & Compartmentalization
6.3Cell Specialization
7Form & Function - Organisms
7.2Transport
7.3Muscle & Motility
8Form & Function - Ecosystems
8.1Species, Communities & Ecosytems
8.3Carbon Cycle
9Interaction & Interdependence - Molecules
9.1Enzymes
9.2Metabolism
9.3Cell Respiration
10Interaction & Interdependence - Cells
10.1Chemical Signalling
10.2Neural Signalling
10.3Adaptation to Environment
10.4Ecological Niches
11Interaction & Interdependence - Organisms
11.1Integration of Body Systems
12Interaction & Interdependence - Ecosystems
12.1Populations & Communities
12.2Transfers of Energy & Matter
13Continuity & Change - Molecules
13.1DNA Replication
13.2Protein Synthesis
14Continuity & Change - Cells
15Continuity & Change - Organisms
15.1Inheritance
15.1.1Non-Nuclear Inheritance
15.1.2Linked Genes
15.1.3IB Multiple Choice - Non-Mendelian Genetics
15.1.4Extended Response - Inheritance
15.1.5Introduction to Non-Mendelian Inheritance
15.1.6Chi-Squared Test
15.1.7End of Topic Quiz - Inheritance
15.1.8Sex-Linked Genes
15.1.9Grade 4-5 (Scientific Practices) - Inheritance
16Continuity & Change - Ecosystems
16.1Natural Selection
16.2Stability & Change
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