Structure of RNA

RNA is usually single-stranded and is made of ribonucleotides that are linked by phosphodiester bonds.

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RNA

  • A ribonucleotide in the RNA chain contains ribose (the pentose sugar), one of the four nitrogenous bases (A, U, G, and C), and the phosphate group.
    • Uracil (U) is a nucleotide only found in RNA. It replaces thymine and pairs with adenine.
    • Uracil is a pyrimidine nucleotide.
  • RNA base sequences are complementary to the DNA's coding sequence from which it has been copied.
  • If the DNA strand has a sequence AATTGCGC, the sequence of the complementary RNA is UUAACGCG.
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Uracil

  • Uracil is a pyrimidine nucleotide found only in RNA. It takes the place of the DNA nucleotide thymine.
  • The RNA base sequence is complementary to the DNA's coding sequence from which it has been copied.
    • If the DNA strand has a sequence AATTGCGC, the sequence of the complementary RNA is UUAACGCG.
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Types of RNA

  • Ribonucleic acid, or RNA, is mainly involved in the process of protein synthesis under the direction of DNA.
  • RNA is usually single-stranded and is made of ribonucleotides that are linked by phosphodiester bonds.
    • There are four major types of RNA: messenger RNA (mRNA), ribosomal RNA (rRNA), transfer RNA (tRNA), and microRNA (miRNA).
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mRNA

  • Messenger RNA (mRNA) carries messages from DNA, which controls all of the cellular activities in a cell.
    • The sequence of nucleotides in mRNA encodes biological information.
  • The RNA base sequence is complementary to the coding sequence of the DNA from which it has been copied.
    • However, in RNA, the base T is absent and U is present instead.
  • The mRNA is read in sets of three bases known as codons.
  • Each codon codes for a single amino acid. In this way, the mRNA is read and the protein product is made.
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tRNA

  • Transfer RNA (tRNA) is one of the smallest of the four types of RNA, usually 70–90 nucleotides long.
  • It carries the correct amino acid to the site of protein synthesis.
    • It is the base pairing between the tRNA and mRNA that allows for the correct amino acid to be inserted in the polypeptide chain.
  • It has an anticodon, which is complementary to the mRNA codon.
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rRNA & miRNA

  • Ribosomal RNA (rRNA) is a major constituent of ribosomes on which the mRNA binds.
    • The rRNA ensures the proper alignment of the mRNA and the ribosomes; the rRNA of the ribosome also has an enzymatic activity (peptidyl transferase) and catalyzes the formation of the peptide bonds between two aligned amino acids.
  • MicroRNAs (miRNAs) are the smallest RNA molecules and their role involves the regulation of gene expression by interfering with the expression of certain mRNA messages

Jump to other topics

1Unity & Diversity - Molecules

2Unity & Diversity - Cells

3Unity & Diversity - Organisms

4Unity & Diversity - Ecosystems

5Form & Function - Molecules

6Form & Function - Cells

7Form & Function - Organisms

8Form & Function - Ecosystems

9Interaction & Interdependence - Molecules

10Interaction & Interdependence - Cells

11Interaction & Interdependence - Organisms

12Interaction & Interdependence - Ecosystems

12.1Populations & Communities

12.2Transfers of Energy & Matter

13Continuity & Change - Molecules

14Continuity & Change - Cells

15Continuity & Change - Organisms

16Continuity & Change - Ecosystems

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