4.8.2
Diffusion
Simple Diffusion
Simple Diffusion
Diffusion is the net movement of particles from an area of high concentration to an area of lower concentration.


Diffusion
Diffusion
- Diffusion describes the passive movement of particles in fluids (liquids and gases).
- Molecules move randomly but tend to move into any space available until it is evenly distributed.
- So, the net movement of particles will be towards the area of lower concentration or down a concentration gradient.
- Substances such as CO2, O2 and urea can move in and out of cells across cell membranes via diffusion.


E.g. Perfume
E.g. Perfume
- When you spray perfume, the smell diffuses across the room from the area of high concentration (where you just sprayed it) to the area of low concentration (the other side of the room).
Facilitated Diffusion
Facilitated Diffusion
In facilitated diffusion, molecules diffuse through carrier proteins or channel proteins spanning across the membrane.


Large or polar molecules
Large or polar molecules
- Some materials are too large to move through the membrane.
- Other materials are polar molecules that are repelled by the hydrophobic part of the membrane.
- These materials move across the membrane by facilitated diffusion.


Facilitated diffusion
Facilitated diffusion
- Facilitated diffusion describes the net movement of particles down a concentration gradient (i.e. from a region of high concentration to a region of lower concentration).
- Facilitated diffusion is a passive process so it does NOT use energy.


Channel proteins
Channel proteins
- Facilitated diffusion takes place through channel proteins.
- Channel proteins allow polar compounds to avoid the non-polar central layer of the plasma membrane.
- The non-polar layer would slow or prevent entry into the cell.
- Aquaporins are channel proteins that allow water to pass through the membrane.


Carrier proteins
Carrier proteins
- Facilitated diffusion takes place through carrier proteins.
- When a substance binds to carrier proteins, there is a change in the shape of the carrier protein.
- This change in shape moves the substance from the outside of the cell to the inside.
Factors Affecting Diffusion
Factors Affecting Diffusion
The rate of diffusion can speed up or slow down based on the following factors:


Concentration gradient
Concentration gradient
- The concentration gradient is linked to the difference in concentration between two areas.
- The bigger the difference in concentration between two areas, the greater the concentration gradient and the faster the rate of diffusion.


Temperature
Temperature
- The higher the temperature, the faster the rate of diffusion.


Membrane surface area
Membrane surface area
- The larger the surface area of the membrane that a substance is diffusing through (e.g. the membrane around a cell), the faster the rate of diffusion.


Thickness of membrane
Thickness of membrane
- The thicker the exchange surface, the slower the rate of diffusion.


Channel or carrier proteins
Channel or carrier proteins
- The higher the concentration gradient, the faster the rate of facilitated diffusion until an equilibrium is reached and the rate will level off.
- The number of channel or carrier proteins affects the rate of facilitated diffusion. The more proteins, the faster the rate.
1Principles of Science I
1.1Structure & Bonding
1.1.1Atomic Model
1.1.2Electron Shells, Sub-Shells & Orbitals
1.1.3Ionic Bonding
1.1.4Representing Ionic Bonds
1.1.5Covalent Bonding
1.1.6Representing Covalent Bonds
1.1.7Metallic Bonding
1.1.8Intermolecular Forces
1.1.9Intermolecular Forces 2
1.1.10End of Topic Test - Bonding
1.1.11Relative Masses
1.1.12The Mole
1.1.13Molar Calculations
1.1.14Molar Calculations 2
1.1.15Empirical & Molecular Formulae
1.1.16Balanced Equations
1.1.17Percentage Yield
1.1.18End of Topic Test - Amount of Substance
1.2Properties of Substances
1.2.1The Periodic Table
1.2.2Ionisation Energy
1.2.3Factors Affecting Ionisation Energies
1.2.4Trends of Ionisation
1.2.5Trends in the Periodic Table
1.2.6Polarity
1.2.7Metals & Non-Metals
1.2.8Alkali Metals
1.2.9Alkaline Earth Metals
1.2.10Reactivity of Alkaline Earth Metals
1.2.11Redox
1.2.12Transition Metals
1.2.13Redox Reactions of Transition Metals
1.3Cell Structure & Function
1.4Cell Specialisation
1.5Tissue Structure & Function
1.5.1Human Gas Exchange
1.5.2Blood Vessels
1.5.3Atherosclerosis
1.5.4Skeletal Muscle
1.5.5Slow & Fast Twitch Fibres
1.5.6Neurones
1.5.7Speed of Transmission
1.5.8Action Potentials
1.5.9End of Topic Test - Neurones & Action Potentials
1.5.10Synapses
1.5.11Types of Synapse
1.5.12Medical Application
1.5.13End of Topic Test - Synapses
1.5.14Chemical Brain Imbalances
1.5.15Effect of Drugs on the Brain
1.6Working with Waves
1.7Waves in Communication
2Practical Scientific Procedures and Techniques
3Science Investigation Skills
3.1Scientific Processes
3.2Data Handling & Analysis
3.3Enzymes in Action
3.4Diffusion
3.5Plants & Their Environment
3.6Energy Content in Fuels
4Principles of Science II
4.1Extracting Elements
4.2Relating Properties to use of Substances
4.3Organic Chemistry
4.4Energy Changes in Industry
4.5The Circulatory System
4.5.1The Circulatory System
4.5.2Blood Vessels
4.5.3Blood Transfusion & the ABO Rhesus System
4.5.4The Heart
4.5.5The Cardiac Cycle
4.5.6Cardiac Output
4.5.7Coordination of Heart Action
4.5.8Heart Dissection
4.5.9Controlling Heart Rate
4.5.10Electrocardiograms
4.5.11Cardiovascular Disease
4.5.12Investigating Heart Rates
4.6Ventilation & Gas Exchange
4.7Urinary System
4.9Thermal Physics
4.9.1Power & Efficiency
4.9.2Work & Energy
4.9.3Conservation of Energy
4.9.4Pressure
4.9.5First Law of Thermodynamics
4.9.6Second Law of Thermodynamics
4.9.7Heat Engines, Heat Pumps & Refrigerators
4.9.8Non-Flow Processes
4.9.9p-V Diagrams
4.9.10Ideal Gases
4.9.11Ideal Gases 2
4.9.12Thermal Energy Transfer
4.9.13Thermal Energy Transfer Experiments
4.10Materials
5Contemporary Issues in Science
5.1Contemporary Issues in Science
5.2Analysing Scientific Information
Jump to other topics
1Principles of Science I
1.1Structure & Bonding
1.1.1Atomic Model
1.1.2Electron Shells, Sub-Shells & Orbitals
1.1.3Ionic Bonding
1.1.4Representing Ionic Bonds
1.1.5Covalent Bonding
1.1.6Representing Covalent Bonds
1.1.7Metallic Bonding
1.1.8Intermolecular Forces
1.1.9Intermolecular Forces 2
1.1.10End of Topic Test - Bonding
1.1.11Relative Masses
1.1.12The Mole
1.1.13Molar Calculations
1.1.14Molar Calculations 2
1.1.15Empirical & Molecular Formulae
1.1.16Balanced Equations
1.1.17Percentage Yield
1.1.18End of Topic Test - Amount of Substance
1.2Properties of Substances
1.2.1The Periodic Table
1.2.2Ionisation Energy
1.2.3Factors Affecting Ionisation Energies
1.2.4Trends of Ionisation
1.2.5Trends in the Periodic Table
1.2.6Polarity
1.2.7Metals & Non-Metals
1.2.8Alkali Metals
1.2.9Alkaline Earth Metals
1.2.10Reactivity of Alkaline Earth Metals
1.2.11Redox
1.2.12Transition Metals
1.2.13Redox Reactions of Transition Metals
1.3Cell Structure & Function
1.4Cell Specialisation
1.5Tissue Structure & Function
1.5.1Human Gas Exchange
1.5.2Blood Vessels
1.5.3Atherosclerosis
1.5.4Skeletal Muscle
1.5.5Slow & Fast Twitch Fibres
1.5.6Neurones
1.5.7Speed of Transmission
1.5.8Action Potentials
1.5.9End of Topic Test - Neurones & Action Potentials
1.5.10Synapses
1.5.11Types of Synapse
1.5.12Medical Application
1.5.13End of Topic Test - Synapses
1.5.14Chemical Brain Imbalances
1.5.15Effect of Drugs on the Brain
1.6Working with Waves
1.7Waves in Communication
2Practical Scientific Procedures and Techniques
3Science Investigation Skills
3.1Scientific Processes
3.2Data Handling & Analysis
3.3Enzymes in Action
3.4Diffusion
3.5Plants & Their Environment
3.6Energy Content in Fuels
4Principles of Science II
4.1Extracting Elements
4.2Relating Properties to use of Substances
4.3Organic Chemistry
4.4Energy Changes in Industry
4.5The Circulatory System
4.5.1The Circulatory System
4.5.2Blood Vessels
4.5.3Blood Transfusion & the ABO Rhesus System
4.5.4The Heart
4.5.5The Cardiac Cycle
4.5.6Cardiac Output
4.5.7Coordination of Heart Action
4.5.8Heart Dissection
4.5.9Controlling Heart Rate
4.5.10Electrocardiograms
4.5.11Cardiovascular Disease
4.5.12Investigating Heart Rates
4.6Ventilation & Gas Exchange
4.7Urinary System
4.9Thermal Physics
4.9.1Power & Efficiency
4.9.2Work & Energy
4.9.3Conservation of Energy
4.9.4Pressure
4.9.5First Law of Thermodynamics
4.9.6Second Law of Thermodynamics
4.9.7Heat Engines, Heat Pumps & Refrigerators
4.9.8Non-Flow Processes
4.9.9p-V Diagrams
4.9.10Ideal Gases
4.9.11Ideal Gases 2
4.9.12Thermal Energy Transfer
4.9.13Thermal Energy Transfer Experiments
4.10Materials
5Contemporary Issues in Science
5.1Contemporary Issues in Science
5.2Analysing Scientific Information
Unlock your full potential with Seneca Premium
Unlimited access to 10,000+ open-ended exam questions
Mini-mock exams based on your study history
Unlock 800+ premium courses & e-books