1.3.2
Prokaryotes
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Prokaryotic Cells
Prokaryotic cells have some features that are also found in eukaryotic cells. Prokaryotic cells may also contain plasmids, a capsule and one or more flagella.

Prokaryotes vs eukaryotes
- Features common to these types of cells are:
- A plasma membrane.
- Cytoplasm.
- DNA.
- Ribosomes (ribosomes are 70S in prokaryotes).
- So, the main difference in terms of organelles is that prokaryotes do NOT have any membrane-bound organelles (e.g. nucleus, mitochondria, Golgi apparatus etc.).

DNA in prokaryotes
- Prokaryotic DNA is found as a circular molecule in the cytoplasm.
- Some prokaryotes have smaller loops of DNA called plasmids that are not part of the main circular DNA molecule.
- Bacteria can exchange plasmids with other bacteria, sometimes receiving beneficial new genes that the recipient can add to their chromosomal DNA.
- Antibiotic resistance is one trait that often spreads through a bacterial colony through plasmid exchange.

Flagella, pili and fimbriae
- Some prokaryotes have flagella, pili, or fimbriae:
- Flagella are tail-like and used for locomotion.
- Some prokaryotes have none and others have more than one.
- Pili are used to exchange genetic material during a type of reproduction called conjugation.
- Fimbriae are used by bacteria to attach to a host cell.
- Flagella are tail-like and used for locomotion.

Capsule & cell wall
- The capsule enables prokaryotic cells to attach to surfaces in its environment.
- Most prokaryotes have a peptidoglycan cell wall.
- The cell wall acts as an extra layer of protection, helps the cell maintain its shape, and prevents dehydration.

Gram staining
- Gram-positive organisms have a thick peptidoglycan layer fortified with teichoic acids.
- Gram-negative organisms have a thin cell wall and an outer envelope containing lipopolysaccharides and lipoproteins.
- The name of these bacteria comes from a lab technique called Gram staining. Gram staining dyes the thick peptidoglycan layer of Gram-positive bacteria purple.
- This purple colour can be seen when stained Gram-positive bacteria are visualised under a light microscope.
- Gram-negative bacteria appear pink/red.

Antibiotics
- Cell walls are an important target for antibiotics.
- Penicillin inhibits the crosslinking of peptidoglycan. This weakens cell walls and causes lysis.
- As both types of bacteria contain peptidoglycan in their cell walls, penicillin is effective against both.
- Some antibiotics only target one type of bacteria.
- Vancomycin is an antibiotic that inhibits the formation of the backbone of Gram-positive cell walls.
- Gram-negative bacteria make their cell walls using a different mechanism, so vancomycin is ineffective.
1Principles of Science I
1.1Structure & Bonding
1.1.1Atomic Model1.1.2Electron Shells, Sub-Shells & Orbitals1.1.3Ionic Bonding1.1.4Representing Ionic Bonds1.1.5Covalent Bonding1.1.6Representing Covalent Bonds1.1.7Metallic Bonding1.1.8Intermolecular Forces1.1.9Intermolecular Forces 21.1.10End of Topic Test - Bonding1.1.11Relative Masses1.1.12The Mole1.1.13Molar Calculations1.1.14Molar Calculations 21.1.15Empirical & Molecular Formulae1.1.16Balanced Equations1.1.17Percentage Yield1.1.18End of Topic Test - Amount of Substance
1.2Properties of Substances
1.2.1The Periodic Table1.2.2Ionisation Energy1.2.3Factors Affecting Ionisation Energies1.2.4Trends of Ionisation1.2.5Trends in the Periodic Table1.2.6Polarity1.2.7Metals & Non-Metals1.2.8Alkali Metals1.2.9Alkaline Earth Metals1.2.10Reactivity of Alkaline Earth Metals1.2.11Redox1.2.12Transition Metals1.2.13Redox Reactions of Transition Metals
1.3Cell Structure & Function
1.4Cell Specialisation
1.5Tissue Structure & Function
1.5.1Human Gas Exchange1.5.2Blood Vessels1.5.3Atherosclerosis1.5.4Skeletal Muscle1.5.5Slow & Fast Twitch Fibres1.5.6Neurones1.5.7Speed of Transmission1.5.8Action Potentials1.5.9End of Topic Test - Neurones & Action Potentials1.5.10Synapses1.5.11Types of Synapse1.5.12Medical Application1.5.13End of Topic Test - Synapses1.5.14Chemical Brain Imbalances1.5.15Effect of Drugs on the Brain
1.6Working with Waves
1.7Waves in Communication
2Practical Scientific Procedures and Techniques
3Science Investigation Skills
3.1Scientific Processes
3.2Data Handling & Analysis
3.3Enzymes in Action
3.4Diffusion
3.5Plants & Their Environment
3.6Energy Content in Fuels
4Principles of Science II
4.1Extracting Elements
4.2Relating Properties to use of Substances
4.3Organic Chemistry
4.4Energy Changes in Industry
4.5The Circulatory System
4.5.1The Circulatory System4.5.2Blood Vessels4.5.3Blood Transfusion & the ABO Rhesus System4.5.4The Heart4.5.5The Cardiac Cycle4.5.6Cardiac Output4.5.7Coordination of Heart Action4.5.8Heart Dissection4.5.9Controlling Heart Rate4.5.10Electrocardiograms4.5.11Cardiovascular Disease4.5.12Investigating Heart Rates
4.6Ventilation & Gas Exchange
4.7Urinary System
4.9Thermal Physics
4.9.1Power & Efficiency4.9.2Work & Energy4.9.3Conservation of Energy4.9.4Pressure4.9.5First Law of Thermodynamics4.9.6Second Law of Thermodynamics4.9.7Heat Engines, Heat Pumps & Refrigerators4.9.8Non-Flow Processes4.9.9p-V Diagrams4.9.10Ideal Gases4.9.11Ideal Gases 24.9.12Thermal Energy Transfer4.9.13Thermal Energy Transfer Experiments
4.10Materials
5Contemporary Issues in Science
5.1Contemporary Issues in Science
5.2Analysing Scientific Information
Jump to other topics
1Principles of Science I
1.1Structure & Bonding
1.1.1Atomic Model1.1.2Electron Shells, Sub-Shells & Orbitals1.1.3Ionic Bonding1.1.4Representing Ionic Bonds1.1.5Covalent Bonding1.1.6Representing Covalent Bonds1.1.7Metallic Bonding1.1.8Intermolecular Forces1.1.9Intermolecular Forces 21.1.10End of Topic Test - Bonding1.1.11Relative Masses1.1.12The Mole1.1.13Molar Calculations1.1.14Molar Calculations 21.1.15Empirical & Molecular Formulae1.1.16Balanced Equations1.1.17Percentage Yield1.1.18End of Topic Test - Amount of Substance
1.2Properties of Substances
1.2.1The Periodic Table1.2.2Ionisation Energy1.2.3Factors Affecting Ionisation Energies1.2.4Trends of Ionisation1.2.5Trends in the Periodic Table1.2.6Polarity1.2.7Metals & Non-Metals1.2.8Alkali Metals1.2.9Alkaline Earth Metals1.2.10Reactivity of Alkaline Earth Metals1.2.11Redox1.2.12Transition Metals1.2.13Redox Reactions of Transition Metals
1.3Cell Structure & Function
1.4Cell Specialisation
1.5Tissue Structure & Function
1.5.1Human Gas Exchange1.5.2Blood Vessels1.5.3Atherosclerosis1.5.4Skeletal Muscle1.5.5Slow & Fast Twitch Fibres1.5.6Neurones1.5.7Speed of Transmission1.5.8Action Potentials1.5.9End of Topic Test - Neurones & Action Potentials1.5.10Synapses1.5.11Types of Synapse1.5.12Medical Application1.5.13End of Topic Test - Synapses1.5.14Chemical Brain Imbalances1.5.15Effect of Drugs on the Brain
1.6Working with Waves
1.7Waves in Communication
2Practical Scientific Procedures and Techniques
3Science Investigation Skills
3.1Scientific Processes
3.2Data Handling & Analysis
3.3Enzymes in Action
3.4Diffusion
3.5Plants & Their Environment
3.6Energy Content in Fuels
4Principles of Science II
4.1Extracting Elements
4.2Relating Properties to use of Substances
4.3Organic Chemistry
4.4Energy Changes in Industry
4.5The Circulatory System
4.5.1The Circulatory System4.5.2Blood Vessels4.5.3Blood Transfusion & the ABO Rhesus System4.5.4The Heart4.5.5The Cardiac Cycle4.5.6Cardiac Output4.5.7Coordination of Heart Action4.5.8Heart Dissection4.5.9Controlling Heart Rate4.5.10Electrocardiograms4.5.11Cardiovascular Disease4.5.12Investigating Heart Rates
4.6Ventilation & Gas Exchange
4.7Urinary System
4.9Thermal Physics
4.9.1Power & Efficiency4.9.2Work & Energy4.9.3Conservation of Energy4.9.4Pressure4.9.5First Law of Thermodynamics4.9.6Second Law of Thermodynamics4.9.7Heat Engines, Heat Pumps & Refrigerators4.9.8Non-Flow Processes4.9.9p-V Diagrams4.9.10Ideal Gases4.9.11Ideal Gases 24.9.12Thermal Energy Transfer4.9.13Thermal Energy Transfer Experiments
4.10Materials
5Contemporary Issues in Science
5.1Contemporary Issues in Science
5.2Analysing Scientific Information
Practice questions on Prokaryotes
Can you answer these? Test yourself with free interactive practice on Seneca — used by over 10 million students.
- 1Common features of prokaryotes:Fill in the list
- 2Which four features do all cells contain?Multiple choice
- 3
- 4
- 5What colour do Gram-positive bacteria appear under a microscope? Multiple choice
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