A-A* (AO3/4) - Translation

Test yourself on A-A* (AO3/4) - Translation

• Discuss the significance of mutations in tRNA and rRNA.

• How does the enzyme reverse transcriptase violate the central dogma of molecular biology in HIV?

• The RNA world hypothesis proposes that the first complex molecule was RNA and it preceded protein formation.
  
  Which major function of the ribosomal RNA best supports the hypothesis?

• A tRNA is chemically modified so that the amino acid bound is different than the one specified by its anticodon.
  
  Which codon in the mRNA would the tRNA recognise: the one specified by its anticodon or the one that matches the modified amino acid it carries?

• Using the peptide encoded by each of the above, compare the three peptides obtained.
  How are peptides 2 and 3 different from 1?