A-A* (AO3/4) - The Cell Cycle

Biology: AQA A Level, topic 2.2.5

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  • Chemotherapy drugs such as vincristine and colchicines disrupt mitosis by binding to tubulin (the subunit of microtubules) and interfering with microtubule assembly and disassembly.

    Exactly what mitotic structure do these drugs target, and what effect would that have on cell division?

  • Compare and contrast a human somatic cell to a human gamete.

  • Which of the following statements about structure 1 on the karyotype is NOT true?

  • Which of the following statements cannot be inferred from the karyotype shown?

  • Based on the karyotype provided, the nondisjunction of which chromosome causes Down syndrome?

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