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Amino Acids

There are about 20 naturally-occurring amino acids in animal cells.

Amino acids

Amino acids

  • Amino acids have the general formula RCH(NH2)COOH.
  • Amino acids contain an acidic group (carboxylic acid) and a basic group (amine) in the same molecule.
    • The -NH2 group is on the carbon next to the -COOH group and so they are known as α-amino acids.
Acid and base behaviour

Acid and base behaviour

  • The -COOH group is acidic and can react with bases by donating a proton (H+).
  • The -NH2 group is basic and can react with acids by accepting a proton (H+).
    • Amino acids are amphoteric because they contain both acidic and basic groups in the same molecule.
Side chain

Side chain

  • An amino acid contains an -R group which is a side chain.
    • This is different for different amino acids.
    • E.g. Alanine has an -R group of -CH3.

Amino Acids as an Acid and Base

Amino acids have the ability to behave as an acid or a base.

Acidic and basic groups

  • In an amino acid:
    • The amine acts as a basic group.
    • The carboxylic acid acts as an acidic group.

Zwitterions 1

  • There is internal movement of an H+ from the carboxylic acid group and onto the amine group to create a zwitterion.
    • The resulting zwitterion has both negative -COO- and positive -NH3+ groups.

Zwitterions 2

  • Zwitterions exist in solids and in solution
  • A zwitterion has no overall charge but parts of the molecule are positively and negatively charged.
Jump to other topics
1

Physical Chemistry

1.1

Atoms, Molecules & Stoichiometry

1.2

Atomic Structure

1.3

Chemical Bonding

1.4

States of Matter

1.5

Chemical Energetics

1.6

Electrochemistry

1.7

Equilibria

1.8

Partition Coefficient

1.9

Reaction Kinetics

2

Inorganic Chemistry

3

Organic Chemistry & Analysis

3.1

Introduction to Organic Chemistry

3.2

Hydrocarbons

3.3

Halogen Derivatives

3.4

Hydroxy Compounds

3.5

Carbonyl Compounds

3.6

Carboxylic Acids & Derivatives

3.7

Nitrogen Compounds

3.8

Polymerisation

3.9

Analytical Techniques

3.10

Organic Synthesis

Practice questions on Amino Acids

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  1. 1
    Amino acids contain:Fill in the list
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    What is a zwitterion?Multiple choice
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