Type I & Type II Diabetes

Type I Diabetes

Diabetes mellitus is a chronic health condition where sufferers cannot properly control their blood glucose concentration. Type I diabetes sufferers cannot produce insulin.

Cause

Type I diabetes is caused when the beta cells in the pancreas are attacked by the immune system.
The beta cells become damaged and can no longer produce insulin.
Some people are more genetically predisposed to type I diabetes than others. It normally develops during childhood.

Hyperglycaemia

Eating causes the blood glucose concentration to increase.
People with type I diabetes cannot produce insulin to counteract the increased levels of glucose so the blood glucose level remains high.
This is called hyperglycaemia.
Hyperglycaemia can lead to death if it is not treated.

Treatment

Insulin therapy is used to treat type I diabetes.
Insulin is injected regularly during the day or an insulin pump can be used continuously.
Too much insulin can cause a fall in glucose levels called hypoglycaemia so insulin therapy must be carefully monitored.

Diet

Controlling intake of glucose is also important to prevent a sudden increase in glucose levels.

Type 2 Diabetes

Type 2 diabetes sufferers don't produce enough insulin or cannot respond to insulin. Type II usually develops later in life than type I.

Cause

Type 2 diabetes is correlated with obesity, lack of exercise, age and family history.
Type 2 diabetes develops when the beta cells in the pancreas no longer produce enough insulin or when the muscle and liver cells stop responding to insulin.

Hyperglycaemia

Type 2 diabetes can lead to hyperglycaemia. This is when blood glucose levels are higher than the optimum level.

Treatment

Type 2 diabetes is treated by eating a healthy diet and exercising.
In some cases, medication is used to lower glucose levels or in rare cases, insulin injections are used.

Preventing Type 2 Diabetes

The food industry has been criticised for its role in contributing to the rise in obesity and consequently type 2 diabetes. Initiatives have been introduced to tackle this growing problem.

Healthy lifestyle

Health advisors recommend a lifestyle that involves:
- A balanced diet that is low in salt, fat and sugar.
- Regular exercise.

Change4life

The NHS 'Change4life' campaign has been introduced.
The campaign educates on how to lead a healthy lifestyle.
The campaign is designed to decrease the risk of developing type II diabetes.

Food content

The World Health Organisation (WHO) recommends that the food industry should help combat the rise in obesity and diabetes by:
- Reducing levels of sugar, saturated fats and salt in processed food products.
- Developing healthy, alternative products.
- Having clear and simple labelling on food items showing the nutritional content (e.g. fat, sugar and salt content).
- Promoting and market healthier foods, especially to children.

1Cell Biology

2Molecular Biology

2.1Water

2.1.1Water & Hydrogen Bonding

2.1.2IB Multiple Choice - Water & Hydrogen Bonding

2.1.3Extended Response - Water

2.2Carbohydrates & Lipids

2.2.1Monosaccharides

2.2.2Disaccharides & Polysaccharides

2.2.3Triglycerides & Phospholipids

2.2.4Cellulose

2.2.5Starch & Glycogen

2.3Proteins

2.3.1Structure & Functions of Proteins

2.4Enzymes

2.4.1Enzymes

2.4.2Factors Affecting Enzyme Activity

2.4.3Enzyme-Controlled Reactions

2.4.4End of Topic Test - Enzymes

2.5Structure of DNA & RNA

2.5.1DNA & RNA

2.6DNA Replication, Transcription & Translation

2.6.1Protein Synthesis

2.6.2Transcription & Translation

2.6.3End of Topic Test - DNA, Genes & Protein Synthesis

2.6.4Exam-Style Question - Protein Synthesis

2.6.5End of Topic Test - Coronavirus Translation

2.6.6IB Multiple Choice - Transcription

2.6.7IB Multiple Choice - Translation

2.7Cell Respiration

2.7.1Overview of Respiration

2.7.2Anaerobic Respiration

2.7.3End of Topic Test - Anaerobic Respiration

2.7.4Respiration Experiments

2.7.5End of Topic Test - Respiration

2.7.6IB Multiple Choice - Respiration

2.8Photosynthesis

2.8.1Overview of Photosynthesis

3Genetics

4Ecology

4.1Species, Communities & Ecosytems

4.1.1Population Dynamics

4.1.2Communities & Measuring Diversity

4.1.3Relationships Between Populations

4.1.4Overview of Ecosystems

4.1.5Nutrient Cycles

4.1.6Fertilisers

4.1.7Eutrophication

4.1.8Chi-Squared Test

4.2Energy Flow

4.2.1Energy

4.2.2Energy Flow

4.2.3Biomass & Food Chains

4.2.4Heterotrophs & Autotrophs

4.3Carbon Cycle

4.3.1Carbon Cycle

4.4Climate Change

4.4.1Carbon Dioxide

4.4.2The Greenhouse Effect

4.4.3Global Warming

4.4.4Maintaining Biodiversity

5Evolution & Biodiversity

5.1Evidence for Evolution

5.1.1Evidence for Evolution - Fossils & DNA

5.1.2Evidence for Evolution - Anatomy & Geography

5.1.3IB Multiple Choice - Evidence for Evolution

5.1.4Extended Response - DNA & Evolution

5.2Natural Selection

5.2.1Introduction

5.2.2Evolutionary Fitness

5.2.3Natural Selection & Variation

5.2.4End of Topic Quiz - Natural Selection

5.2.5IB Multiple Choice - Natural Selection

5.2.6Speciation

5.3Classification of Biodiversity

5.3.1Introduction to Biodiversity

5.3.2Keystone Species

5.3.3Courtship & Ancestry

5.3.4Classification

5.4Cladistics

5.4.1Evolutionary Relationships

5.4.2IB Multiple Choice - Species & Taxonomy

6Human Physiology

6.1Digestion & Absorption

6.1.1Overview of Digestion

6.1.2Digestion in Mammals

6.1.3Absorption

6.1.4End of Topic Test - Substance Exchange & Digestion

6.1.5End of Topic Test - Substance Ex & Digestion

6.2The Blood System

6.2.1The Circulatory System

6.2.2The Heart

6.2.3Blood Vessels

6.2.4Cardiovascular Disease

6.3Defence Against Infectious Disease

6.3.1Immune System

6.3.2The Immune Response

6.3.3Antibodies

6.3.4Primary & Secondary Response

6.3.5Vaccines

6.3.6HIV

6.3.7End of Topic Test - Immune System

6.3.8Exam-Style Question - Immune System

6.3.9End of Topic Test - Immune System

6.4Gas Exchange

6.4.1Lung Structure & Alveoli

6.4.2Ventilation

6.4.3Lung Disease

6.4.4Lung Disease Data

6.5Neurons & Synapses

6.5.1Neuron Structure

6.5.2Transmission of an Impulse

6.5.3Speed of Transmission

6.5.4End of Topic Test - Neurones & Action Potentials

6.5.5Synapses

6.5.6Types of Synapse

6.5.7Medical Application

6.5.8End of Topic Test - Synapses

6.5.9End of Topic Test - Nervous Comm&Coord

6.6Hormones, HomeoStasis & Reproduction

6.6.1Overview of Homeostasis

6.6.2Blood Glucose Concentration

6.6.3Controlling Blood Glucose Concentration

6.6.4End of Topic Test - Blood Glucose

6.6.5Type I & Type II Diabetes

6.6.6Human Reproductive Systems

6.6.7Hormonal Control of the Menstrual Cycle

7AHL: Nucleic Acids

7.1DNA Structure & Replication

7.1.1DNA

7.1.2RNA

7.1.3DNA Replication

7.1.4DNA Replication - Summary

7.1.5IB Multiple Choice - DNA Replication

7.2Transcription & Gene Expression

7.2.1Introduction to Transcription & Protein Synthesis

7.2.2Types of RNA

7.2.3Transcription

7.2.4RNA Processing in Eukaryotes

7.2.5IB Multiple Choice - Transcription

7.3Translation

7.3.1Translation

7.3.2Retroviruses

7.3.3Scientific Practices: Coronavirus

7.3.4IB Multiple Choice - Translation

8AHL: Metabolism, Cell Respiration & Photosynthesis

8.1Metabolism

8.1.1Molecules to Metabolism

8.2Cell Respiration

8.2.1Glycolysis

8.2.2Aerobic Respiration

8.3Photosynthesis

8.3.1Light-Dependent Reaction

8.3.2Light-Independent Reaction

8.3.3End of Topic Test - Photosynthesis Reactions

8.3.4Limiting Factors

8.3.5Photosynthesis Experiments

8.3.6End of Topic Test - Photosynthesis

8.3.7End of Topic Test - Photosynthesis

9AHL: Plant Biology

9.1Transport in the Xylem of Plants

9.1.1Structure

9.1.2Cohesion-Tension Theory

9.1.3Investigating Transpiration Rate

9.2Transport in the Phloem of Plants

9.2.1Structure

9.2.2Translocation

9.3Growth in Plants

9.3.1Plant Tropisms

10AHL: Genetics & Evolution

10.1Meiosis

10.1.1Stages of Meiosis

10.2Inheritance

10.2.1Linked Genes

10.2.2Sex-Linked Genes

10.2.3Non-Nuclear Inheritance

10.2.4Chi-Squared Test

10.2.5End of Topic Quiz - Inheritance

10.2.6IB Multiple Choice - Non-Mendelian Genetics

10.2.7Introduction to Non-Mendelian Inheritance

10.2.8Extended Response - Inheritance

10.2.9Grade 4-5 (Scientific Practices) - Inheritance

10.3Gene Pools & Speciation

10.3.1Populations

10.3.2Mutations, Genetic Drift, & Gene Flow

10.3.3Speciation

10.3.4Rate of Speciation

10.3.5Allopatric & Sympatric Speciation

11AHL: Animal Physiology

11.1Antibody Production & Vaccination

11.1.1Immune System

11.1.2The Immune Response

11.1.3Antibodies

11.1.4Primary & Secondary Response

11.1.5Vaccines

11.2Movement

11.2.1Skeletal Muscle

11.2.2Sliding Filament Theory

11.2.3Contraction

11.3The Kidney & Osmoregulation

11.3.1Kidneys & Osmoregulation

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