3.4.3

Mendelian Laws

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Mendel's Laws

Genetics is the science of heredity. Austrian monk Gregor Mendel proposed that genes are inherited as pairs of alleles that behave in a dominant and recessive pattern and came up with several "laws":

Illustrative background for Mendel’s law of dominanceIllustrative background for Mendel’s law of dominance ?? "content

Mendel’s law of dominance

  • This law states that in a heterozygote, one trait will conceal the presence of another trait for the same characteristic.
    • Rather than both alleles contributing to a phenotype, the dominant allele will be expressed exclusively.
  • The recessive allele will remain “latent” but will be transmitted to offspring by the same manner in which the dominant allele is transmitted.
  • The recessive trait will only be expressed by offspring that have two copies of this allele.
Illustrative background for Mendel’s law of segregation Illustrative background for Mendel’s law of segregation  ?? "content

Mendel’s law of segregation

  • Mendel observed that breeding together two heterozygotes produced offspring that expressed the dominant and recessive traits in a 3:1 ratio.
  • Mendel used this finding to propose the law of segregation.
    • This law states that paired unit factors (genes) must segregate equally into gametes such that offspring have an equal likelihood of inheriting either factor.
  • This law can be illustrated by using a monohybrid cross, and will be covered in a subsequent unit.
Illustrative background for Physical basis of segregationIllustrative background for Physical basis of segregation ?? "content

Physical basis of segregation

  • The physical basis of Mendel’s law of segregation is the first division of meiosis.
  • In this division, the homologous chromosomes with their different versions of each gene are segregated into daughter nuclei.
    • The role of the meiotic segregation of chromosomes in sexual reproduction was not understood by the scientific community during Mendel’s lifetime.
Illustrative background for Law of independent assortmentIllustrative background for Law of independent assortment ?? "content

Law of independent assortment

  • Mendel’s law of independent assortment states that genes do not influence each other with regard to the sorting of alleles into gametes, and every possible combination of alleles for every gene is equally likely to occur.
    • This law can be illustrated by using a dihybrid cross, and will be covered in a subsequent unit.

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