Meiosis
Biology: Cambridge International A Level, topic 16.1.1
Role of Meiosis
Meiosis is the process that produces haploid gamete cells from diploid cells. Meiosis is necessary for sexual reproduction to take place.

Sexual reproduction
- Gametes are the sex cells (e.g. sperm cells and egg cells) that fuse together during sexual reproduction.
- Gametes are haploid (contain one chromosome).
- When the gametes fuse together, a new diploid organism (an organism with two copies of every chromosome) is formed.
- An individual inherits one copy of a chromosome from each parent.
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Producing gametes
- Haploid gametes are produced from diploid cells in an organism.
- The gametes are produced in a process called meiosis.
- Meiosis involves two sequential cell divisions (meiosis I and meiosis II).
- In humans, meiosis is used to produce sperm and egg cells.
- In plants, microspore cells divide by meiosis to produce pollen grains (plant gametes).

Genetic variation
- Meiosis produces four genetically different daughter cells.
- Each daughter cell receives a different combination of chromosomes.
- Meiosis increases genetic diversity in this way.
Meiosis
Meiosis is the production of haploid gametes from diploid cells. The steps involved in this process are:

1) Interphase + prophase 1
- Interphase:
- The chromosomes in the cells replicate to produce an identical copy of each other.
- The replicated chromosomes are called chromatids.
- Prophase 1:
- The chromatids condense to form a double-armed chromosome. Each arm is made from one chromatid and is joined by a centromere.
- Each arm is called a sister chromatid.

2) Metaphase 1
- Chromosomes in diploid organisms are found in homologous pairs (chromosomes with identical genes but different alleles).
- The chromosomes in a pair are arranged in the center of the cell.
- The chromosomes are moved by fibers called spindle fibers.

3) Anaphase 1 + telophase 1
- Anaphase 1:
- The homologous chromosomes are separated and pulled to opposite ends of the cell by the spindle fibers.
- The separation of the chromosomes from each pair is random.
- Telophase 1:
- Random combinations of chromosomes are pulled to each side of the cell.

4) Cytokinesis (end of meiosis 1)
- As the homologous chromosomes are separated, the cell divides into two cells.
- One chromosome from a pair is separated into each cell.
- This division concludes meiosis 1.
- Meiosis 1 produces two genetically different cells.

5) Prophase 2 + metaphase 2
- Prophase 2:
- The chromatids condense again.
- Metaphase 2:
- Chromosomes line up in the center of the cell.

6) Anaphase 2
- Anaphase 2:
- The sister chromatids are separated by the spindle fibers and pulled to opposite ends of the cell.
- The separation of the sister chromatids is random.
7) Telophase 2 + cytokinesis
- As the sister chromatids are separated, the cell divides into two cells.
- One chromatid from a chromosome is separated into each cell.
- This division concludes meiosis 2.
- Meiosis 2 produces four genetically different haploid cells.
Test yourself on Meiosis
Which of the following statements about meiosis are true?
What is the role of meiosis?
How many chromosomes does a human gamete have if a body cell has 46?
Stages Involved in Meiosis
Which of the following statements about meiosis are true?