3.1.1

Germ Theory

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Germ Theory and the Work of Pasteur

Before Louis Pasteur’s work in 1861, there was a debate over how infections were spread. Before Pasteur, most scientists believed spontaneous generation and that diseases could be spread by miasma or contact.

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Spontaneous generation

  • Surgeons thought that microbes were caused by disease in something called “spontaneous generation”.
    • The microbes were a symptom and diseases developed randomly, creating bacteria.
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Spreading disease

  • The two main groups were contagionists and anti-contagionists.
    • Contagionists believed disease could spread through contact.
    • Anti-contagionists believed disease spread through miasma.
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Pasteur

  • In 1857, Pasteur tried to explain why the sugar beet used to ferment alcohol soured. Pasteur thought that germs in the air were responsible.
  • He found that sterilised water was still sterile if the flask was closed, but was not sterile if the flask was open. This suggested that there were germs in the air.
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Germ Theory

  • In 1861, he published his theory – germs were causing infections.
  • Microscopes (invented in the 17th century) eventually allowed Pasteur to see the micro-organisms that he described.
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Opposition to Germ Theory

  • Pasteur faced serious opposition for his theory.
  • A famous doctor called Charlton Bastian supported the theory of spontaneous generation, which contradicted Pasteur’s Germ Theory.
  • Pasteur’s research focused on how liquids, such as milk went sour (pasteurisation). Many did not see the connection to humans.
    • Doctors did not believe that small germs could cause such harm to humans.

The Impact of Germ Theory on Medical Treatment

Germ Theory could be applied to everyday medical treatments.

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Everyday medical treatments

  • People gradually began to believe (and treat people in accordance with) Germ Theory.
    • Most of the gains from Germ Theory came in the 20th century.
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Implications of Germ Theory

  • It proved that disease was not spread by miasma.
  • It proved that spontaneous generation was wrong.
  • It proved that an imbalance of the Four Humours did not cause disease, thus meaning the Four Humours were wrong.
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Safer medical treatment

  • In 19th century Britain, medical treatments became safer.
    • The survival rate in surgery increased, hospitals became cleaner and vaccinations became more popular.
  • Technological developments meant that diseases could be identified and stopped more effectively.
    • Following Germ Theory, drugs were developed and became far more popular.

Jump to other topics

1Medicine in Medieval England

2The Medical Renaissance in England

3Medicine in 18th & 19th Century Britain

4Medicine in Modern Britain

5Treatment in WW1

6Themes in Medicine

7Some Extra Context (Not Compulsory for Exam)

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