Source: https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-2-effects-of-mutations [Revision notes](https://senecalearning.com/en-gb/revision-notes.md) › [A Level](https://senecalearning.com/en-gb/revision-notes/a-level.md) › [Biology](https://senecalearning.com/en-gb/revision-notes/a-level/biology.md) › [AQA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa.md) › Effects of Mutations # Effects of Mutations Biology: AQA A Level, topic 8.1.2 ## Effects of Mutation The sequence of bases in DNA encodes the amino acids that are used in protein synthesis. If this sequence is altered by mutation, this could influence the proteins an organism produces. ### Encoding amino acids ![Encoding amino acids](https://image-v2.cdn.app.senecalearning.com/2018-09/528469d3-bd79-47ab-8019-b29ec9df5c94/DNA-triplets-codon-mrna-.jpg) - There are four different bases in DNA (A, T, C, G). - Three bases in a sequence encode an amino acid. This is called the triplet code or a codon. - Every codon encodes a different amino acid. - Amino acids are joined together to form proteins. ### Protein 3D structure ![Protein 3D structure](https://image-v2.cdn.app.senecalearning.com/2018-09/2ba93ac0-3cba-489d-b5e7-983e601179c3/Quaternary-Structure-Protein-polypeptide-.jpg) - Every amino acid has a side chain (called the R group) that differs slightly. - The bonds that can form between the R groups of different amino acids within a protein can give rise to a complex 3D structure. - The 3D structure of proteins is very important for their function (e.g. the shape of an enzyme active site is determine by its amino acids). ### Mutations ![Mutations](https://image-v2.cdn.app.senecalearning.com/2018-09/48fc7302-b92e-40d3-a186-a881da4a0ce3/Tertiary-Structure-Protein-polypeptide-.jpg) - Mutations give rise to a change in the base sequence in DNA. - This could alter the amino acids that the DNA encodes. - E.g. CTG encodes leucine. If this was inverted to GTC, it would encode valine. - If the amino acids in a protein are changed, the 3D structure of the protein may break down. ### Effect of mutation ![Effect of mutation](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/5.2.1%20-%20The%20nervous%20system/protein-min.jpg) - If a protein's structure is affected by a mutation, this could have harmful effects. - Some genetic disorders are caused by mutations in this way. - E.g. Cystic fibrosis is caused by a mutation that affects proteins in the epithelial cells of the respiratory system. ## The Degenerate Code Some mutations have no effect on protein structure because of the degenerate nature of DNA. This is because some amino acids are encoded by more than one base triplet code. ### Triplet codes ![Triplet codes](https://image-v2.cdn.app.senecalearning.com/2018-09/528469d3-bd79-47ab-8019-b29ec9df5c94/DNA-triplets-codon-mrna-.jpg) - Some amino acids are encoded by more than one codon (e.g. tyrosine is encoded by TAT and TAC). - The fact that some amino acids correspond to multiple codons means that DNA is degenerate. ### Mutations ![Mutations](https://image-v2.cdn.app.senecalearning.com/2018-09/51d6d6e8-8550-4bb4-8a47-2ac3099ca9a0/amino%20acids-degenerate-code-dna-.png) - The fact that DNA is degenerate means that a mutation in the base sequence does not necessarily affect the protein. - If one base is substituted for another base, (e.g. CAA → CAG), the mutated codon may still encode the same amino acid (e.g. both encode glutamine). ## Frameshift Sometimes a mutation can have a very large impact on the protein structure if it impacts all the base triplets downstream from the mutation. This is called a frameshift. ### Causes of a frameshift ![Causes of a frameshift](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/6.1.2%20-%20DNA/DNA%20base%20structure%20(1)%20-%20Edited%20(1)-min.png) - A frameshift is caused when a base (or multiple bases) is inserted, removed or duplicated into the genome. - This type of mutation has altered the number of bases in the DNA sequence. - This means that all the triplet codes downstream from the mutation will experience a shift. ### Effects of a frameshift ![Effects of a frameshift](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/5.2.1%20-%20The%20nervous%20system/protein-min.jpg) - A frameshift causes all amino acids that follow the mutation to be affected. - If only one amino acid in a protein is changed in a mutation, the protein may be able to function as normal. - A frameshift impacts many amino acids so it is much less likely that the protein will function as normal. ### E.g. Crohn's disease ![E.g. Crohn's disease](https://image-v2.cdn.app.senecalearning.com/2018-09/bf8653ca-b246-40fc-890c-a62b7008bd30/bowels-intestines.png) - Crohn's disease is an inflammatory bowel disease that is caused by a frameshift mutation. - When Cytosine is inserted at position 3020 of the NOD2 gene, the subsequent codons are shifted. - This causes the protein to be shortened and it cannot function properly. ## Test yourself on Effects of Mutations - Which of the following statements about mutations are true? - Stages in the Effects of a Mutation - Why is the DNA said to be degenerate? - Which of the following statements about frameshifts are true? - Which of the following mutations would NOT cause a frameshift? [Practise this topic for free](https://app.senecalearning.com/classroom/course/d0ce0c30-6417-11e8-8edc-d9cd1c890408/section/eb55cacc-2012-4705-8ff2-6990c53f3126/session) - Previous topic: [8.1.1 Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-1-mutations.md) - Next topic: [8.1.3 Causes of Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-3-causes-of-mutations.md) ## Biology: AQA A Level contents ### 1 Biological Molecules - 1.1 Monomers & Polymers - [1.1.1 Monomers & Polymers](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-1-1-monomers-and-polymers.md) - [1.1.2 Condensation & Hydrolysis Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-1-2-condensation-and-hydrolysis-reactions.md) - 1.2 Carbohydrates - [1.2.1 Structure of Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-1-structure-of-carbohydrates.md) - [1.2.2 Types of Polysaccharides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-2-types-of-polysaccharides.md) - [1.2.3 End of Topic Test - Monomers, Polymers and Carbs](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-3-end-of-topic-test-monomers-polymers-and-carbs.md) - [1.2.4 Exam-Style Question - Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-4-exam-style-question-carbohydrates.md) - [1.2.5 A-A* (AO3/4) - Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-5-a-a-ao34-carbohydrates.md) - 1.3 Lipids - [1.3.1 Triglycerides & Phospholipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-1-triglycerides-and-phospholipids.md) - [1.3.2 Types of Fatty Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-2-types-of-fatty-acids.md) - [1.3.3 Testing for Lipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-3-testing-for-lipids.md) - [1.3.4 Exam-Style Question - Fats](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-4-exam-style-question-fats.md) - [1.3.5 A-A* (AO3/4) - Lipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-5-a-a-ao34-lipids.md) - 1.4 Proteins - [1.4.1 The Peptide Chain](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-1-the-peptide-chain.md) - [1.4.2 Investigating Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-2-investigating-proteins.md) - [1.4.3 Primary & Secondary Protein Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-3-primary-and-secondary-protein-structure.md) - [1.4.4 Tertiary & Quaternary Protein Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-4-tertiary-and-quaternary-protein-structure.md) - [1.4.5 Enzymes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-5-enzymes.md) - [1.4.6 Factors Affecting Enzyme Activity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-6-factors-affecting-enzyme-activity.md) - [1.4.7 Enzyme-Controlled Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-7-enzyme-controlled-reactions.md) - [1.4.8 End of Topic Test - Lipids & Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-8-end-of-topic-test-lipids-and-proteins.md) - [1.4.9 A-A* (AO3/4) - Enzymes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-9-a-a-ao34-enzymes.md) - [1.4.10 A-A* (AO3/4) - Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-10-a-a-ao34-proteins.md) - [1.4.11 Diagnostic Misconceptions - Enzyme Inhibitors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-11-diagnostic-misconceptions-enzyme-inhibitors.md) - 1.5 Nucleic Acids - [1.5.1 DNA & RNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-1-dna-and-rna.md) - [1.5.2 Nucleotides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-2-nucleotides.md) - [1.5.3 Polynucleotides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-3-polynucleotides.md) - [1.5.4 DNA Replication](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-4-dna-replication.md) - [1.5.5 Exam-Style Question - Nucleic Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-5-exam-style-question-nucleic-acids.md) - [1.5.6 A-A* (AO3/4) - Nucleic Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-6-a-a-ao34-nucleic-acids.md) - 1.6 ATP - [1.6.1 Structure of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-1-structure-of-atp.md) - [1.6.2 Hydrolysis of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-2-hydrolysis-of-atp.md) - [1.6.3 Resynthesis of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-3-resynthesis-of-atp.md) - [1.6.4 End of Topic Test - Nucleic Acids & ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-4-end-of-topic-test-nucleic-acids-and-atp.md) - 1.7 Water - [1.7.1 Importance of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-1-importance-of-water.md) - [1.7.2 Structure of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-2-structure-of-water.md) - [1.7.3 Properties of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-3-properties-of-water.md) - [1.7.4 A-A* (AO3/4) - Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-4-a-a-ao34-water.md) - 1.8 Inorganic Ions - [1.8.1 Inorganic Ions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-8-1-inorganic-ions.md) - [1.8.2 End of Topic Test - Water & Inorganic Ions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-8-2-end-of-topic-test-water-and-inorganic-ions.md) ### 2 Cells - 2.1 Cell Structure - [2.1.1 Introduction to Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-1-introduction-to-cells.md) - [2.1.2 Eukaryotic Cells & Organelles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-2-eukaryotic-cells-and-organelles.md) - [2.1.3 Eukaryotic Cells & Organelles 2](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-3-eukaryotic-cells-and-organelles-2.md) - [2.1.4 Prokaryotes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-4-prokaryotes.md) - [2.1.5 A-A* (AO3/4) - Organelles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-5-a-a-ao34-organelles.md) - [2.1.6 Methods of Studying Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-6-methods-of-studying-cells.md) - [2.1.7 Microscopes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-7-microscopes.md) - [2.1.8 End of Topic Test - Cell Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-8-end-of-topic-test-cell-structure.md) - [2.1.9 Exam-Style Question - Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-9-exam-style-question-cells.md) - [2.1.10 A-A* (AO3/4) - Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-10-a-a-ao34-cells.md) - 2.2 Mitosis & Cancer - [2.2.1 Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-1-mitosis.md) - [2.2.2 Stages of Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-2-stages-of-mitosis.md) - [2.2.3 Investigating Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-3-investigating-mitosis.md) - [2.2.4 Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-4-cancer.md) - [2.2.5 A-A* (AO3/4) - The Cell Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-5-a-a-ao34-the-cell-cycle.md) - 2.3 Transport Across Cell Membrane - [2.3.1 Cell Membrane Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-1-cell-membrane-structure.md) - [2.3.2 A-A* (AO3/4) - Membrane Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-2-a-a-ao34-membrane-structure.md) - [2.3.3 Diffusion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-3-diffusion.md) - [2.3.4 Osmosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-4-osmosis.md) - [2.3.5 Active Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-5-active-transport.md) - [2.3.6 End of Topic Test - Mitosis, Cancer & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-6-end-of-topic-test-mitosis-cancer-and-transport.md) - [2.3.7 Exam-Style Question - Membranes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-7-exam-style-question-membranes.md) - [2.3.8 A-A* (AO3/4) - Membranes & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-8-a-a-ao34-membranes-and-transport.md) - [2.3.9 A-A*- Mitosis, Cancer & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-9-a-a-mitosis-cancer-and-transport.md) - 2.4 Cell Recognition & the Immune System - [2.4.1 Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-1-immune-system.md) - [2.4.2 Phagocytosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-2-phagocytosis.md) - [2.4.3 T Lymphocytes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-3-t-lymphocytes.md) - [2.4.4 B Lymphocytes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-4-b-lymphocytes.md) - [2.4.5 Antibodies](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-5-antibodies.md) - [2.4.6 Primary & Secondary Response](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-6-primary-and-secondary-response.md) - [2.4.7 Vaccines](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-7-vaccines.md) - [2.4.8 HIV](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-8-hiv.md) - [2.4.9 Ethical Issues](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-9-ethical-issues.md) - [2.4.10 End of Topic Test - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-10-end-of-topic-test-immune-system.md) - [2.4.11 Exam-Style Question - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-11-exam-style-question-immune-system.md) - [2.4.12 A-A* (AO3/4) - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-12-a-a-ao34-immune-system.md) - [2.4.13 Diagnostic Misconceptions - Humoral vs Cellular](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-13-diagnostic-misconceptions-humoral-vs-cellular.md) ### 3 Substance Exchange - 3.1 Surface Area to Volume Ratio - [3.1.1 Size & Surface Area](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-1-1-size-and-surface-area.md) - [3.1.2 A-A* (AO3/4) - Cell Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-1-2-a-a-ao34-cell-size.md) - 3.2 Gas Exchange - [3.2.1 Single-Celled Organisms](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-1-single-celled-organisms.md) - [3.2.2 Multicellular Organisms](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-2-multicellular-organisms.md) - [3.2.3 Control of Water Loss](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-3-control-of-water-loss.md) - [3.2.4 Human Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-4-human-gas-exchange.md) - [3.2.5 Ventilation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-5-ventilation.md) - [3.2.6 Dissection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-6-dissection.md) - [3.2.7 Measuring Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-7-measuring-gas-exchange.md) - [3.2.8 Lung Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-8-lung-disease.md) - [3.2.9 Lung Disease Data](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-9-lung-disease-data.md) - [3.2.10 End of Topic Test - Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-10-end-of-topic-test-gas-exchange.md) - [3.2.11 A-A* (AO3/4) - Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-11-a-a-ao34-gas-exchange.md) - 3.3 Digestion & Absorption - [3.3.1 Overview of Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-1-overview-of-digestion.md) - [3.3.2 Digestion in Mammals](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-2-digestion-in-mammals.md) - [3.3.3 Absorption](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-3-absorption.md) - [3.3.4 End of Topic Test - Substance Exchange & Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-4-end-of-topic-test-substance-exchange-and-digestion.md) - [3.3.5 A-A* (AO3/4) - Substance Ex & Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-5-a-a-ao34-substance-ex-and-digestion.md) - 3.4 Mass Transport - [3.4.1 Haemoglobin](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-1-haemoglobin.md) - [3.4.2 Oxygen Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-2-oxygen-transport.md) - [3.4.3 The Circulatory System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-3-the-circulatory-system.md) - [3.4.4 The Heart](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-4-the-heart.md) - [3.4.5 Blood Vessels](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-5-blood-vessels.md) - [3.4.6 Cardiovascular Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-6-cardiovascular-disease.md) - [3.4.7 Heart Dissection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-7-heart-dissection.md) - [3.4.8 Xylem](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-8-xylem.md) - [3.4.9 Phloem](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-9-phloem.md) - [3.4.10 Investigating Plant Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-10-investigating-plant-transport.md) - [3.4.11 End of Topic Test - Mass Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-11-end-of-topic-test-mass-transport.md) - [3.4.12 A-A* (AO3/4) - Mass Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-12-a-a-ao34-mass-transport.md) - [3.4.13 Diagnostic Misconceptions - Concentration Gradient](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-13-diagnostic-misconceptions-concentration-gradient.md) - [3.4.14 Diagnostic Misconceptions - Cardiac Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-14-diagnostic-misconceptions-cardiac-cycle.md) - [3.4.15 Diagnostic Misconceptions - Carrying Capacity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-15-diagnostic-misconceptions-carrying-capacity.md) - [3.4.16 Diagnostic Misconceptions - Translocation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-16-diagnostic-misconceptions-translocation.md) ### 4 Genetic Information & Variation - 4.1 DNA, Genes & Chromosomes - [4.1.1 DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-1-dna.md) - [4.1.2 Genes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-2-genes.md) - [4.1.3 Non-Coding Genes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-3-non-coding-genes.md) - [4.1.4 The Genetic Code](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-4-the-genetic-code.md) - [4.1.5 A-A* (AO3/4) - DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-5-a-a-ao34-dna.md) - 4.2 DNA & Protein Synthesis - [4.2.1 Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-1-protein-synthesis.md) - [4.2.2 Transcription & Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-2-transcription-and-translation.md) - [4.2.3 End of Topic Test - DNA, Genes & Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-3-end-of-topic-test-dna-genes-and-protein-synthesis.md) - [4.2.4 Exam-Style Question - Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-4-exam-style-question-protein-synthesis.md) - [4.2.5 A-A* (AO3/4) - Coronavirus Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-5-a-a-ao34-coronavirus-translation.md) - [4.2.6 A-A* (AO3/4) - Transcription](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-6-a-a-ao34-transcription.md) - [4.2.7 A-A* (AO3/4) - Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-7-a-a-ao34-translation.md) - 4.3 Mutations & Meiosis - [4.3.1 Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-1-mutations.md) - [4.3.2 Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-2-meiosis.md) - [4.3.3 A-A* (AO3/4) - Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-3-a-a-ao34-meiosis.md) - [4.3.4 Meiosis vs Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-4-meiosis-vs-mitosis.md) - [4.3.5 End of Topic Test - Mutations, Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-5-end-of-topic-test-mutations-meiosis.md) - [4.3.6 A-A* (AO3/4) - DNA,Genes, CellDiv & ProtSynth](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-6-a-a-ao34-dnagenes-celldiv-and-protsynth.md) - [4.3.7 Diagnostic Misconceptions - Meiosis vs Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-7-diagnostic-misconceptions-meiosis-vs-mitosis.md) - 4.4 Genetic Diversity & Adaptation - [4.4.1 Genetic Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-1-genetic-diversity.md) - [4.4.2 Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-2-natural-selection.md) - [4.4.3 A-A* (AO3/4) - Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-3-a-a-ao34-natural-selection.md) - [4.4.4 Adaptations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-4-adaptations.md) - [4.4.5 Investigating Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-5-investigating-natural-selection.md) - [4.4.6 End of Topic Test - Genetic Diversity & Adaptation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-6-end-of-topic-test-genetic-diversity-and-adaptation.md) - [4.4.7 A-A* (AO3/4) - Genetic Diversity & Adaptation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-7-a-a-ao34-genetic-diversity-and-adaptation.md) - 4.5 Species & Taxonomy - [4.5.1 Courtship Behaviour](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-1-courtship-behaviour.md) - [4.5.2 Phylogeny](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-2-phylogeny.md) - [4.5.3 Classification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-3-classification.md) - [4.5.4 DNA Technology](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-4-dna-technology.md) - [4.5.5 A-A* (AO3/4) - Species & Taxonomy](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-5-a-a-ao34-species-and-taxonomy.md) - 4.6 Biodiversity Within a Community - [4.6.1 Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-1-biodiversity.md) - [4.6.2 Index of diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-2-index-of-diversity.md) - [4.6.3 Agriculture](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-3-agriculture.md) - [4.6.4 End of Topic Test - Species,Taxonomy& Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-4-end-of-topic-test-speciestaxonomyand-biodiversity.md) - [4.6.5 A-A* (AO3/4) - Species,Taxon&Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-5-a-a-ao34-speciestaxonandbiodiversity.md) - 4.7 Investigating Diversity - [4.7.1 Genetic Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-7-1-genetic-diversity.md) - [4.7.2 Quantitative Investigation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-7-2-quantitative-investigation.md) ### 5 Energy Transfers (A2 only) - 5.1 Photosynthesis - [5.1.1 Overview of Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-1-overview-of-photosynthesis.md) - [5.1.2 Photoionisation of Chlorophyll](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-2-photoionisation-of-chlorophyll.md) - [5.1.3 Production of ATP & Reduced NADP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-3-production-of-atp-and-reduced-nadp.md) - [5.1.4 Cyclic Photophosphorylation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-4-cyclic-photophosphorylation.md) - [5.1.5 Light-Independent Reaction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-5-light-independent-reaction.md) - [5.1.6 A-A* (AO3/4) - Photosynthesis Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-6-a-a-ao34-photosynthesis-reactions.md) - [5.1.7 Limiting Factors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-7-limiting-factors.md) - [5.1.8 Photosynthesis Experiments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-8-photosynthesis-experiments.md) - [5.1.9 End of Topic Test - Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-9-end-of-topic-test-photosynthesis.md) - [5.1.10 A-A* (AO3/4) - Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-10-a-a-ao34-photosynthesis.md) - 5.2 Respiration - [5.2.1 Overview of Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-1-overview-of-respiration.md) - [5.2.2 Anaerobic Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-2-anaerobic-respiration.md) - [5.2.3 A-A* (AO3/4) - Anaerobic Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-3-a-a-ao34-anaerobic-respiration.md) - [5.2.4 The Link Reaction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-4-the-link-reaction.md) - [5.2.5 The Krebs Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-5-the-krebs-cycle.md) - [5.2.6 Oxidative Phosphorylation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-6-oxidative-phosphorylation.md) - [5.2.7 Respiration Experiments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-7-respiration-experiments.md) - [5.2.8 End of Topic Test - Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-8-end-of-topic-test-respiration.md) - [5.2.9 A-A* (AO3/4) - Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-9-a-a-ao34-respiration.md) - [5.2.10 Diagnostic Misconceptions - Aerobic vs Anaerobic](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-10-diagnostic-misconceptions-aerobic-vs-anaerobic.md) - 5.3 Energy & Ecosystems - [5.3.1 Biomass](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-1-biomass.md) - [5.3.2 Production & Productivity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-2-production-and-productivity.md) - [5.3.3 Agricultural Practices](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-3-agricultural-practices.md) - 5.4 Nutrient Cycles - [5.4.1 Nitrogen Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-1-nitrogen-cycle.md) - [5.4.2 Phosphorous Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-2-phosphorous-cycle.md) - [5.4.3 Fertilisers & Eutrophication](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-3-fertilisers-and-eutrophication.md) - [5.4.4 End of Topic Test - Nutrient Cycles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-4-end-of-topic-test-nutrient-cycles.md) - [5.4.5 A-A* (AO3/4) - Energy,Ecosystems&NutrientCycles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-5-a-a-ao34-energyecosystemsandnutrientcycles.md) ### 6 Responding to Change (A2 only) - 6.1 Nervous Communication - [6.1.1 Survival](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-1-survival.md) - [6.1.2 Plant Responses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-2-plant-responses.md) - [6.1.3 Animal Responses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-3-animal-responses.md) - [6.1.4 Reflexes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-4-reflexes.md) - [6.1.5 End of Topic Test - Reflexes, Responses & Survival](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-5-end-of-topic-test-reflexes-responses-and-survival.md) - [6.1.6 Receptors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-6-receptors.md) - [6.1.7 The Human Retina](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-7-the-human-retina.md) - [6.1.8 Control of Heart Rate](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-8-control-of-heart-rate.md) - [6.1.9 End of Topic Test - Receptors, Retina & Heart Rate](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-9-end-of-topic-test-receptors-retina-and-heart-rate.md) - 6.2 Nervous Coordination - [6.2.1 Neurones](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-1-neurones.md) - [6.2.2 Action Potentials](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-2-action-potentials.md) - [6.2.3 Speed of Transmission](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-3-speed-of-transmission.md) - [6.2.4 End of Topic Test - Neurones & Action Potentials](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-4-end-of-topic-test-neurones-and-action-potentials.md) - [6.2.5 Synapses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-5-synapses.md) - [6.2.6 Types of Synapse](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-6-types-of-synapse.md) - [6.2.7 Medical Application](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-7-medical-application.md) - [6.2.8 End of Topic Test - Synapses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-8-end-of-topic-test-synapses.md) - [6.2.9 A-A* (AO3/4) - Nervous Comm&Coord](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-9-a-a-ao34-nervous-commandcoord.md) - 6.3 Muscle Contraction - [6.3.1 Skeletal Muscle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-1-skeletal-muscle.md) - [6.3.2 Sliding Filament Theory](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-2-sliding-filament-theory.md) - [6.3.3 Contraction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-3-contraction.md) - [6.3.4 Slow & Fast Twitch Fibres](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-4-slow-and-fast-twitch-fibres.md) - [6.3.5 End of Topic Test - Muscles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-5-end-of-topic-test-muscles.md) - [6.3.6 A-A* (AO3/4) - Muscle Contraction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-6-a-a-ao34-muscle-contraction.md) - 6.4 Homeostasis - [6.4.1 Overview of Homeostasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-1-overview-of-homeostasis.md) - [6.4.2 Blood Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-2-blood-glucose-concentration.md) - [6.4.3 Controlling Blood Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-3-controlling-blood-glucose-concentration.md) - [6.4.4 End of Topic Test - Blood Glucose](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-4-end-of-topic-test-blood-glucose.md) - [6.4.5 Primary & Secondary Messengers](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-5-primary-and-secondary-messengers.md) - [6.4.6 Diabetes Mellitus](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-6-diabetes-mellitus.md) - [6.4.7 Measuring Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-7-measuring-glucose-concentration.md) - [6.4.8 Osmoregulation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-8-osmoregulation.md) - [6.4.9 Controlling Blood Water Potential](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-9-controlling-blood-water-potential.md) - [6.4.10 ADH](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-10-adh.md) - [6.4.11 End of Topic Test - Diabetes & Osmoregulation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-11-end-of-topic-test-diabetes-and-osmoregulation.md) - [6.4.12 A-A* (AO3/4) - Homeostasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-12-a-a-ao34-homeostasis.md) - [6.4.13 Diagnostic Misconceptions - Effect of ADH](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-13-diagnostic-misconceptions-effect-of-adh.md) ### 7 Genetics & Ecosystems (A2 only) - 7.1 Genetics - [7.1.1 Key Terms in Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-1-key-terms-in-genetics.md) - [7.1.2 Inheritance](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-2-inheritance.md) - [7.1.3 Linkage](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-3-linkage.md) - [7.1.4 Multiple Alleles & Epistasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-4-multiple-alleles-and-epistasis.md) - [7.1.5 Chi-Squared Test](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-5-chi-squared-test.md) - [7.1.6 End of Topic Test - Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-6-end-of-topic-test-genetics.md) - [7.1.7 A-A* (AO3/4) - Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-7-a-a-ao34-genetics.md) - [7.1.8 Diagnostic Misconceptions - Dihybrid Inheritance](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-8-diagnostic-misconceptions-dihybrid-inheritance.md) - [7.1.9 Diagnostic Misconceptions - Sex Linkage](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-9-diagnostic-misconceptions-sex-linkage.md) - 7.2 Populations - [7.2.1 Populations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-2-1-populations.md) - [7.2.2 Hardy-Weinberg Principle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-2-2-hardy-weinberg-principle.md) - 7.3 Evolution - [7.3.1 Variation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-1-variation.md) - [7.3.2 Natural Selection & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-2-natural-selection-and-evolution.md) - [7.3.3 End of Topic Test - Populations & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-3-end-of-topic-test-populations-and-evolution.md) - [7.3.4 Types of Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-4-types-of-selection.md) - [7.3.5 Types of Selection Summary](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-5-types-of-selection-summary.md) - [7.3.6 Overview of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-6-overview-of-speciation.md) - [7.3.7 Causes of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-7-causes-of-speciation.md) - [7.3.8 Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-8-diversity.md) - [7.3.9 End of Topic Test - Selection & Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-9-end-of-topic-test-selection-and-speciation.md) - [7.3.10 A-A* (AO3/4) - Populations & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-10-a-a-ao34-populations-and-evolution.md) - [7.3.11 Diagnostic Misconceptions - Types of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-11-diagnostic-misconceptions-types-of-speciation.md) - 7.4 Populations in Ecosystems - [7.4.1 Overview of Ecosystems](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-1-overview-of-ecosystems.md) - [7.4.2 Niche](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-2-niche.md) - [7.4.3 Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-3-population-size.md) - [7.4.4 Investigating Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-4-investigating-population-size.md) - [7.4.5 End of Topic Test - Ecosystems & Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-5-end-of-topic-test-ecosystems-and-population-size.md) - [7.4.6 Succession](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-6-succession.md) - [7.4.7 Conservation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-7-conservation.md) - [7.4.8 End of Topic Test - Succession & Conservation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-8-end-of-topic-test-succession-and-conservation.md) - [7.4.9 A-A* (AO3/4) - Ecosystems](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-9-a-a-ao34-ecosystems.md) ### 8 The Control of Gene Expression (A2 only) - 8.1 Mutation - [8.1.1 Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-1-mutations.md) - [8.1.2 Effects of Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-2-effects-of-mutations.md) - [8.1.3 Causes of Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-3-causes-of-mutations.md) - [8.1.4 Diagnostic Misconceptions - Gene Expression](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-4-diagnostic-misconceptions-gene-expression.md) - 8.2 Gene Expression - [8.2.1 Stem Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-1-stem-cells.md) - [8.2.2 Stem Cells in Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-2-stem-cells-in-disease.md) - [8.2.3 End of Topic Test - Mutation & Gene Epression](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-3-end-of-topic-test-mutation-and-gene-epression.md) - [8.2.4 A-A* (AO3/4) - Mutation & Stem Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-4-a-a-ao34-mutation-and-stem-cells.md) - [8.2.5 Regulating Transcription](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-5-regulating-transcription.md) - [8.2.6 Epigenetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-6-epigenetics.md) - [8.2.7 Epigenetics & Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-7-epigenetics-and-disease.md) - [8.2.8 Regulating Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-8-regulating-translation.md) - [8.2.9 Experimental Data](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-9-experimental-data.md) - [8.2.10 End of Topic Test - Transcription & Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-10-end-of-topic-test-transcription-and-translation.md) - [8.2.11 Tumours](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-11-tumours.md) - [8.2.12 Correlations & Causes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-12-correlations-and-causes.md) - [8.2.13 Prevention & Treatment](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-13-prevention-and-treatment.md) - [8.2.14 End of Topic Test - Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-14-end-of-topic-test-cancer.md) - [8.2.15 A-A* (AO3/4) - Gene Expression & Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-15-a-a-ao34-gene-expression-and-cancer.md) - 8.3 Genome Projects - [8.3.1 Using Genome Projects](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-3-1-using-genome-projects.md) - 8.4 Gene Technology - [8.4.1 Recombinant DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-1-recombinant-dna.md) - [8.4.2 Producing Fragments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-2-producing-fragments.md) - [8.4.3 Amplification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-3-amplification.md) - [8.4.4 End of Topic Test - Genome Project & Amplification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-4-end-of-topic-test-genome-project-and-amplification.md) - [8.4.5 Using Recombinant DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-5-using-recombinant-dna.md) - [8.4.6 Medical Diagnosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-6-medical-diagnosis.md) - [8.4.7 Genetic Fingerprinting](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-7-genetic-fingerprinting.md) - [8.4.8 End of Topic Test - Gene Technologies](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-8-end-of-topic-test-gene-technologies.md) - [8.4.9 A-A* (AO3/4) - Gene Technology](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-9-a-a-ao34-gene-technology.md) ### 9 Mathematical Skills - 9.1 Mathematical Skills - [9.1.1 Diagnostic Misconceptions - Converting Units](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-1-diagnostic-misconceptions-converting-units.md) - [9.1.2 Diagnostic Misconceptions - Correct Hypothesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-2-diagnostic-misconceptions-correct-hypothesis.md) - [9.1.3 Diagnostic Misconceptions - Interpret Hypothesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-3-diagnostic-misconceptions-interpret-hypothesis.md) - [9.1.4 Diagnostic Misconceptions - Calculate Uncertainty](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-4-diagnostic-misconceptions-calculate-uncertainty.md)