Source: https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-6-factors-affecting-enzyme-activity

[Revision notes](https://senecalearning.com/en-gb/revision-notes.md) › [A Level](https://senecalearning.com/en-gb/revision-notes/a-level.md) › [Biology](https://senecalearning.com/en-gb/revision-notes/a-level/biology.md) › [AQA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa.md) › Factors Affecting Enzyme Activity

# Factors Affecting Enzyme Activity

Biology: AQA A Level, topic 1.4.6

## Investigating Rates of Enzyme-Controlled Reactions

Changes to the tertiary structure of an enzyme through changing the pH or temperature will affect how fast reactions are catalysed.

### Temperature

![Temperature](https://image-v2.cdn.app.senecalearning.com/courseImages/physics/2.2.1%20Thermal%20expansion/thermometer-869392_640-min.jpg)

- Increasing the temperature will increase the kinetic energy of the molecules.
- This increases the chance of a collision between the enzyme and substrate and so more collisions are likely in a set period of time. In other words, the rate of reaction is faster.
- Increasing the temperature by 10oC will approximately double the rate of reaction for most enzyme-controlled reactions.

### pH

![pH](https://image-v2.cdn.app.senecalearning.com/courseImages/chemistry/Edexcel/5%20Acids,%20Alkalis,%20pH/universal_indicator.jpg)

- Changing the pH changes the number of hydroxide ions and hydrogen ions (OH− and H+) surrounding the enzyme.
- These interact with the charges on the enzyme’s amino acids, affecting hydrogen bonding and ionic bonding, so resulting in changes to the tertiary structure.

### Denatured enzymes

![Denatured enzymes](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/2.2.5%20denatured%20enzyme%20(s).png)

- Increasing or decreasing the temperature or pH outside of an optimal range can affect chemical bonds within the active site and the enzyme will not work as well. 
 - At extreme temperatures and pH values, the enzyme's structure may be changed. This is called a denatured enzyme.

## Enzyme and Substrate Concentration

Reaction rate is influenced by the relative enzyme and substrate concentrations.

### Enzyme concentration

![Enzyme concentration](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/2.2.1%20-%20Enzymes%201/protein.jpg)

- Increasing the concentration of enzyme in a solution means there are more enzyme molecules available to catalyse the substrate in a given amount of time

### Substrate concentration

![Substrate concentration](https://image-v2.cdn.app.senecalearning.com/courseImages/biology/Edexcel/1%20Cells/1.2.1.2%20-%20Substrate%20concentration.png)

- Increasing the concentration of the substrate increases the numbers of substrate molecules that can form enzyme-substrate (ES) complexes at any one time. 
- This increases the initial rate of reaction but when all the enzyme molecules are engaged in ES complexes the rate cannot increase any further.  
- The rate will then plateau because the enzyme is said to be saturated.

## Inhibition of Enzyme Activity

Reaction rate is influenced by the presence of competitive and non-competitive inhibitors.

### Function of competitive inhibitors

![Function of competitive inhibitors](https://image-v2.cdn.app.senecalearning.com/2018-09/e55d7e3e-4bac-4435-9873-5e5d429927d7/Competitive-Inhibitor-Graph-inhibition-.jpg)

- Inhibitors are chemicals that slow down the rate or stop the reaction altogether.
- Enzyme-substrate complexes cannot be formed or are formed at a much lower rate.

### Structure of competitive inhibitors

![Structure of competitive inhibitors](https://image-v2.cdn.app.senecalearning.com/2018-11/0310d58e-d664-4ea0-9330-f0bf84da72c3/competitive-inhibitor-enzyme.png)

- Competitive inhibitors are similar in shape to the usual substrate and affect the active site directly, blocking access for the formation of ES complexes.
- Increasing the substrate concentration can compensate for the effects of a competitive inhibitor as there is no permanent damage to the shape of the active site.
 - Malonate ions are similar in shape to succinate ions and act as a competitive inhibitor of succinate dehydrogenase, an important enzyme in the Krebs cycle.

### Function of non-competitive inhibitors

![Function of non-competitive inhibitors](https://image-v2.cdn.app.senecalearning.com/2018-09/21da7937-d925-4651-9e36-5a4abd5bda4b/Non-competitive-inhibitor-graph-inhibition-.jpg)

- Some non-competitive inhibitors have reversible effect but others are irreversible and denature the enzyme.
 - E.g. Lead denatures a number of enzymes required to synthesise haemoglobin.

### Structure of non-competitive inhibitors

![Structure of non-competitive inhibitors](https://image-v2.cdn.app.senecalearning.com/2018-11/0310d58e-d664-4ea0-9330-f0bf84da72c3/competitive-inhibitor-enzyme.png)

- Non-competitive inhibitors affect another part of the enzyme molecule causing a change to the shape of the active site. 
- The active site is no longer complementary to the substrate molecules.

## Test yourself on Factors Affecting Enzyme Activity

- Which of the following statements about temperature and pH are true?
- What is the effect of increasing temperature on enzyme function?
- What is the impact of a 10°C increase in temperature on the rate of reaction, assuming that the new temperature is still in the optimum range of the enzyme?
- Which of the following statements about enzyme and substrate concentration are true?
- What happens to the rate of reaction when the enzymes become saturated?

[Practise this topic for free](https://app.senecalearning.com/classroom/course/d0ce0c30-6417-11e8-8edc-d9cd1c890408/section/2ab15e9a-c570-4cb6-ab3b-8b0a0672211b/session)

- Previous topic: [1.4.5 Enzymes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-5-enzymes.md)
- Next topic: [1.4.7 Enzyme-Controlled Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-7-enzyme-controlled-reactions.md)

## Biology: AQA A Level contents

### 1 Biological Molecules
- 1.1 Monomers & Polymers
  - [1.1.1 Monomers & Polymers](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-1-1-monomers-and-polymers.md)
  - [1.1.2 Condensation & Hydrolysis Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-1-2-condensation-and-hydrolysis-reactions.md)
- 1.2 Carbohydrates
  - [1.2.1 Structure of Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-1-structure-of-carbohydrates.md)
  - [1.2.2 Types of Polysaccharides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-2-types-of-polysaccharides.md)
  - [1.2.3 End of Topic Test - Monomers, Polymers and Carbs](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-3-end-of-topic-test-monomers-polymers-and-carbs.md)
  - [1.2.4 Exam-Style Question - Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-4-exam-style-question-carbohydrates.md)
  - [1.2.5 A-A* (AO3/4) - Carbohydrates](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-2-5-a-a-ao34-carbohydrates.md)
- 1.3 Lipids
  - [1.3.1 Triglycerides & Phospholipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-1-triglycerides-and-phospholipids.md)
  - [1.3.2 Types of Fatty Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-2-types-of-fatty-acids.md)
  - [1.3.3 Testing for Lipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-3-testing-for-lipids.md)
  - [1.3.4 Exam-Style Question - Fats](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-4-exam-style-question-fats.md)
  - [1.3.5 A-A* (AO3/4) - Lipids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-3-5-a-a-ao34-lipids.md)
- 1.4 Proteins
  - [1.4.1 The Peptide Chain](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-1-the-peptide-chain.md)
  - [1.4.2 Investigating Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-2-investigating-proteins.md)
  - [1.4.3 Primary & Secondary Protein Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-3-primary-and-secondary-protein-structure.md)
  - [1.4.4 Tertiary & Quaternary Protein Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-4-tertiary-and-quaternary-protein-structure.md)
  - [1.4.5 Enzymes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-5-enzymes.md)
  - [1.4.6 Factors Affecting Enzyme Activity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-6-factors-affecting-enzyme-activity.md)
  - [1.4.7 Enzyme-Controlled Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-7-enzyme-controlled-reactions.md)
  - [1.4.8 End of Topic Test - Lipids & Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-8-end-of-topic-test-lipids-and-proteins.md)
  - [1.4.9 A-A* (AO3/4) - Enzymes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-9-a-a-ao34-enzymes.md)
  - [1.4.10 A-A* (AO3/4) - Proteins](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-10-a-a-ao34-proteins.md)
  - [1.4.11 Diagnostic Misconceptions - Enzyme Inhibitors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-4-11-diagnostic-misconceptions-enzyme-inhibitors.md)
- 1.5 Nucleic Acids
  - [1.5.1 DNA & RNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-1-dna-and-rna.md)
  - [1.5.2 Nucleotides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-2-nucleotides.md)
  - [1.5.3 Polynucleotides](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-3-polynucleotides.md)
  - [1.5.4 DNA Replication](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-4-dna-replication.md)
  - [1.5.5 Exam-Style Question - Nucleic Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-5-exam-style-question-nucleic-acids.md)
  - [1.5.6 A-A* (AO3/4) - Nucleic Acids](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-5-6-a-a-ao34-nucleic-acids.md)
- 1.6 ATP
  - [1.6.1 Structure of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-1-structure-of-atp.md)
  - [1.6.2 Hydrolysis of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-2-hydrolysis-of-atp.md)
  - [1.6.3 Resynthesis of ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-3-resynthesis-of-atp.md)
  - [1.6.4 End of Topic Test - Nucleic Acids & ATP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-6-4-end-of-topic-test-nucleic-acids-and-atp.md)
- 1.7 Water
  - [1.7.1 Importance of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-1-importance-of-water.md)
  - [1.7.2 Structure of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-2-structure-of-water.md)
  - [1.7.3 Properties of Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-3-properties-of-water.md)
  - [1.7.4 A-A* (AO3/4) - Water](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-7-4-a-a-ao34-water.md)
- 1.8 Inorganic Ions
  - [1.8.1 Inorganic Ions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-8-1-inorganic-ions.md)
  - [1.8.2 End of Topic Test - Water & Inorganic Ions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/1-8-2-end-of-topic-test-water-and-inorganic-ions.md)

### 2 Cells
- 2.1 Cell Structure
  - [2.1.1 Introduction to Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-1-introduction-to-cells.md)
  - [2.1.2 Eukaryotic Cells & Organelles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-2-eukaryotic-cells-and-organelles.md)
  - [2.1.3 Eukaryotic Cells & Organelles 2](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-3-eukaryotic-cells-and-organelles-2.md)
  - [2.1.4 Prokaryotes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-4-prokaryotes.md)
  - [2.1.5 A-A* (AO3/4) - Organelles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-5-a-a-ao34-organelles.md)
  - [2.1.6 Methods of Studying Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-6-methods-of-studying-cells.md)
  - [2.1.7 Microscopes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-7-microscopes.md)
  - [2.1.8 End of Topic Test - Cell Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-8-end-of-topic-test-cell-structure.md)
  - [2.1.9 Exam-Style Question - Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-9-exam-style-question-cells.md)
  - [2.1.10 A-A* (AO3/4) - Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-1-10-a-a-ao34-cells.md)
- 2.2 Mitosis & Cancer
  - [2.2.1 Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-1-mitosis.md)
  - [2.2.2 Stages of Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-2-stages-of-mitosis.md)
  - [2.2.3 Investigating Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-3-investigating-mitosis.md)
  - [2.2.4 Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-4-cancer.md)
  - [2.2.5 A-A* (AO3/4) - The Cell Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-2-5-a-a-ao34-the-cell-cycle.md)
- 2.3 Transport Across Cell Membrane
  - [2.3.1 Cell Membrane Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-1-cell-membrane-structure.md)
  - [2.3.2 A-A* (AO3/4) - Membrane Structure](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-2-a-a-ao34-membrane-structure.md)
  - [2.3.3 Diffusion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-3-diffusion.md)
  - [2.3.4 Osmosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-4-osmosis.md)
  - [2.3.5 Active Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-5-active-transport.md)
  - [2.3.6 End of Topic Test - Mitosis, Cancer & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-6-end-of-topic-test-mitosis-cancer-and-transport.md)
  - [2.3.7 Exam-Style Question - Membranes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-7-exam-style-question-membranes.md)
  - [2.3.8 A-A* (AO3/4) - Membranes & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-8-a-a-ao34-membranes-and-transport.md)
  - [2.3.9 A-A*- Mitosis, Cancer & Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-3-9-a-a-mitosis-cancer-and-transport.md)
- 2.4 Cell Recognition & the Immune System
  - [2.4.1 Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-1-immune-system.md)
  - [2.4.2 Phagocytosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-2-phagocytosis.md)
  - [2.4.3 T Lymphocytes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-3-t-lymphocytes.md)
  - [2.4.4 B Lymphocytes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-4-b-lymphocytes.md)
  - [2.4.5 Antibodies](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-5-antibodies.md)
  - [2.4.6 Primary & Secondary Response](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-6-primary-and-secondary-response.md)
  - [2.4.7 Vaccines](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-7-vaccines.md)
  - [2.4.8 HIV](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-8-hiv.md)
  - [2.4.9 Ethical Issues](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-9-ethical-issues.md)
  - [2.4.10 End of Topic Test - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-10-end-of-topic-test-immune-system.md)
  - [2.4.11 Exam-Style Question - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-11-exam-style-question-immune-system.md)
  - [2.4.12 A-A* (AO3/4) - Immune System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-12-a-a-ao34-immune-system.md)
  - [2.4.13 Diagnostic Misconceptions - Humoral vs Cellular](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/2-4-13-diagnostic-misconceptions-humoral-vs-cellular.md)

### 3 Substance Exchange
- 3.1 Surface Area to Volume Ratio
  - [3.1.1 Size & Surface Area](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-1-1-size-and-surface-area.md)
  - [3.1.2 A-A* (AO3/4) - Cell Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-1-2-a-a-ao34-cell-size.md)
- 3.2 Gas Exchange
  - [3.2.1 Single-Celled Organisms](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-1-single-celled-organisms.md)
  - [3.2.2 Multicellular Organisms](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-2-multicellular-organisms.md)
  - [3.2.3 Control of Water Loss](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-3-control-of-water-loss.md)
  - [3.2.4 Human Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-4-human-gas-exchange.md)
  - [3.2.5 Ventilation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-5-ventilation.md)
  - [3.2.6 Dissection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-6-dissection.md)
  - [3.2.7 Measuring Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-7-measuring-gas-exchange.md)
  - [3.2.8 Lung Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-8-lung-disease.md)
  - [3.2.9 Lung Disease Data](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-9-lung-disease-data.md)
  - [3.2.10 End of Topic Test - Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-10-end-of-topic-test-gas-exchange.md)
  - [3.2.11 A-A* (AO3/4) - Gas Exchange](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-2-11-a-a-ao34-gas-exchange.md)
- 3.3 Digestion & Absorption
  - [3.3.1 Overview of Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-1-overview-of-digestion.md)
  - [3.3.2 Digestion in Mammals](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-2-digestion-in-mammals.md)
  - [3.3.3 Absorption](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-3-absorption.md)
  - [3.3.4 End of Topic Test - Substance Exchange & Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-4-end-of-topic-test-substance-exchange-and-digestion.md)
  - [3.3.5 A-A* (AO3/4) - Substance Ex & Digestion](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-3-5-a-a-ao34-substance-ex-and-digestion.md)
- 3.4 Mass Transport
  - [3.4.1 Haemoglobin](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-1-haemoglobin.md)
  - [3.4.2 Oxygen Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-2-oxygen-transport.md)
  - [3.4.3 The Circulatory System](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-3-the-circulatory-system.md)
  - [3.4.4 The Heart](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-4-the-heart.md)
  - [3.4.5 Blood Vessels](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-5-blood-vessels.md)
  - [3.4.6 Cardiovascular Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-6-cardiovascular-disease.md)
  - [3.4.7 Heart Dissection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-7-heart-dissection.md)
  - [3.4.8 Xylem](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-8-xylem.md)
  - [3.4.9 Phloem](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-9-phloem.md)
  - [3.4.10 Investigating Plant Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-10-investigating-plant-transport.md)
  - [3.4.11 End of Topic Test - Mass Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-11-end-of-topic-test-mass-transport.md)
  - [3.4.12 A-A* (AO3/4) - Mass Transport](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-12-a-a-ao34-mass-transport.md)
  - [3.4.13 Diagnostic Misconceptions - Concentration Gradient](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-13-diagnostic-misconceptions-concentration-gradient.md)
  - [3.4.14 Diagnostic Misconceptions - Cardiac Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-14-diagnostic-misconceptions-cardiac-cycle.md)
  - [3.4.15 Diagnostic Misconceptions - Carrying Capacity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-15-diagnostic-misconceptions-carrying-capacity.md)
  - [3.4.16 Diagnostic Misconceptions - Translocation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/3-4-16-diagnostic-misconceptions-translocation.md)

### 4 Genetic Information & Variation
- 4.1 DNA, Genes & Chromosomes
  - [4.1.1 DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-1-dna.md)
  - [4.1.2 Genes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-2-genes.md)
  - [4.1.3 Non-Coding Genes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-3-non-coding-genes.md)
  - [4.1.4 The Genetic Code](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-4-the-genetic-code.md)
  - [4.1.5 A-A* (AO3/4) - DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-1-5-a-a-ao34-dna.md)
- 4.2 DNA & Protein Synthesis
  - [4.2.1 Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-1-protein-synthesis.md)
  - [4.2.2 Transcription & Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-2-transcription-and-translation.md)
  - [4.2.3 End of Topic Test - DNA, Genes & Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-3-end-of-topic-test-dna-genes-and-protein-synthesis.md)
  - [4.2.4 Exam-Style Question - Protein Synthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-4-exam-style-question-protein-synthesis.md)
  - [4.2.5 A-A* (AO3/4) - Coronavirus Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-5-a-a-ao34-coronavirus-translation.md)
  - [4.2.6 A-A* (AO3/4) - Transcription](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-6-a-a-ao34-transcription.md)
  - [4.2.7 A-A* (AO3/4) - Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-2-7-a-a-ao34-translation.md)
- 4.3 Mutations & Meiosis
  - [4.3.1 Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-1-mutations.md)
  - [4.3.2 Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-2-meiosis.md)
  - [4.3.3 A-A* (AO3/4)  - Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-3-a-a-ao34-meiosis.md)
  - [4.3.4 Meiosis vs Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-4-meiosis-vs-mitosis.md)
  - [4.3.5 End of Topic Test - Mutations, Meiosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-5-end-of-topic-test-mutations-meiosis.md)
  - [4.3.6 A-A* (AO3/4) - DNA,Genes, CellDiv & ProtSynth](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-6-a-a-ao34-dnagenes-celldiv-and-protsynth.md)
  - [4.3.7 Diagnostic Misconceptions - Meiosis vs Mitosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-3-7-diagnostic-misconceptions-meiosis-vs-mitosis.md)
- 4.4 Genetic Diversity & Adaptation
  - [4.4.1 Genetic Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-1-genetic-diversity.md)
  - [4.4.2 Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-2-natural-selection.md)
  - [4.4.3 A-A* (AO3/4) - Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-3-a-a-ao34-natural-selection.md)
  - [4.4.4 Adaptations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-4-adaptations.md)
  - [4.4.5 Investigating Natural Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-5-investigating-natural-selection.md)
  - [4.4.6 End of Topic Test - Genetic Diversity & Adaptation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-6-end-of-topic-test-genetic-diversity-and-adaptation.md)
  - [4.4.7 A-A* (AO3/4) - Genetic Diversity & Adaptation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-4-7-a-a-ao34-genetic-diversity-and-adaptation.md)
- 4.5 Species & Taxonomy
  - [4.5.1 Courtship Behaviour](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-1-courtship-behaviour.md)
  - [4.5.2 Phylogeny](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-2-phylogeny.md)
  - [4.5.3 Classification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-3-classification.md)
  - [4.5.4 DNA Technology](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-4-dna-technology.md)
  - [4.5.5 A-A* (AO3/4) - Species & Taxonomy](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-5-5-a-a-ao34-species-and-taxonomy.md)
- 4.6 Biodiversity Within a Community
  - [4.6.1 Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-1-biodiversity.md)
  - [4.6.2 Index of diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-2-index-of-diversity.md)
  - [4.6.3 Agriculture](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-3-agriculture.md)
  - [4.6.4 End of Topic Test - Species,Taxonomy& Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-4-end-of-topic-test-speciestaxonomyand-biodiversity.md)
  - [4.6.5 A-A* (AO3/4) - Species,Taxon&Biodiversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-6-5-a-a-ao34-speciestaxonandbiodiversity.md)
- 4.7 Investigating Diversity
  - [4.7.1 Genetic Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-7-1-genetic-diversity.md)
  - [4.7.2 Quantitative Investigation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/4-7-2-quantitative-investigation.md)

### 5 Energy Transfers (A2 only)
- 5.1 Photosynthesis
  - [5.1.1 Overview of Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-1-overview-of-photosynthesis.md)
  - [5.1.2 Photoionisation of Chlorophyll](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-2-photoionisation-of-chlorophyll.md)
  - [5.1.3 Production of ATP & Reduced NADP](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-3-production-of-atp-and-reduced-nadp.md)
  - [5.1.4 Cyclic Photophosphorylation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-4-cyclic-photophosphorylation.md)
  - [5.1.5 Light-Independent Reaction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-5-light-independent-reaction.md)
  - [5.1.6 A-A* (AO3/4) - Photosynthesis Reactions](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-6-a-a-ao34-photosynthesis-reactions.md)
  - [5.1.7 Limiting Factors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-7-limiting-factors.md)
  - [5.1.8 Photosynthesis Experiments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-8-photosynthesis-experiments.md)
  - [5.1.9 End of Topic Test - Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-9-end-of-topic-test-photosynthesis.md)
  - [5.1.10 A-A* (AO3/4) - Photosynthesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-1-10-a-a-ao34-photosynthesis.md)
- 5.2 Respiration
  - [5.2.1 Overview of Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-1-overview-of-respiration.md)
  - [5.2.2 Anaerobic Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-2-anaerobic-respiration.md)
  - [5.2.3 A-A* (AO3/4) - Anaerobic Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-3-a-a-ao34-anaerobic-respiration.md)
  - [5.2.4 The Link Reaction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-4-the-link-reaction.md)
  - [5.2.5 The Krebs Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-5-the-krebs-cycle.md)
  - [5.2.6 Oxidative Phosphorylation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-6-oxidative-phosphorylation.md)
  - [5.2.7 Respiration Experiments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-7-respiration-experiments.md)
  - [5.2.8 End of Topic Test - Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-8-end-of-topic-test-respiration.md)
  - [5.2.9 A-A* (AO3/4) - Respiration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-9-a-a-ao34-respiration.md)
  - [5.2.10 Diagnostic Misconceptions - Aerobic vs Anaerobic](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-2-10-diagnostic-misconceptions-aerobic-vs-anaerobic.md)
- 5.3 Energy & Ecosystems
  - [5.3.1 Biomass](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-1-biomass.md)
  - [5.3.2 Production & Productivity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-2-production-and-productivity.md)
  - [5.3.3 Agricultural Practices](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-3-3-agricultural-practices.md)
- 5.4 Nutrient Cycles
  - [5.4.1 Nitrogen Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-1-nitrogen-cycle.md)
  - [5.4.2 Phosphorous Cycle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-2-phosphorous-cycle.md)
  - [5.4.3 Fertilisers & Eutrophication](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-3-fertilisers-and-eutrophication.md)
  - [5.4.4 End of Topic Test - Nutrient Cycles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-4-end-of-topic-test-nutrient-cycles.md)
  - [5.4.5 A-A* (AO3/4) - Energy,Ecosystems&NutrientCycles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/5-4-5-a-a-ao34-energyecosystemsandnutrientcycles.md)

### 6 Responding to Change (A2 only)
- 6.1 Nervous Communication
  - [6.1.1 Survival](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-1-survival.md)
  - [6.1.2 Plant Responses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-2-plant-responses.md)
  - [6.1.3 Animal Responses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-3-animal-responses.md)
  - [6.1.4 Reflexes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-4-reflexes.md)
  - [6.1.5 End of Topic Test - Reflexes, Responses & Survival](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-5-end-of-topic-test-reflexes-responses-and-survival.md)
  - [6.1.6 Receptors](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-6-receptors.md)
  - [6.1.7 The Human Retina](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-7-the-human-retina.md)
  - [6.1.8 Control of Heart Rate](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-8-control-of-heart-rate.md)
  - [6.1.9 End of Topic Test - Receptors, Retina & Heart Rate](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-1-9-end-of-topic-test-receptors-retina-and-heart-rate.md)
- 6.2 Nervous Coordination
  - [6.2.1 Neurones](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-1-neurones.md)
  - [6.2.2 Action Potentials](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-2-action-potentials.md)
  - [6.2.3 Speed of Transmission](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-3-speed-of-transmission.md)
  - [6.2.4 End of Topic Test - Neurones & Action Potentials](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-4-end-of-topic-test-neurones-and-action-potentials.md)
  - [6.2.5 Synapses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-5-synapses.md)
  - [6.2.6 Types of Synapse](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-6-types-of-synapse.md)
  - [6.2.7 Medical Application](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-7-medical-application.md)
  - [6.2.8 End of Topic Test - Synapses](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-8-end-of-topic-test-synapses.md)
  - [6.2.9 A-A* (AO3/4) - Nervous Comm&Coord](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-2-9-a-a-ao34-nervous-commandcoord.md)
- 6.3 Muscle Contraction
  - [6.3.1 Skeletal Muscle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-1-skeletal-muscle.md)
  - [6.3.2 Sliding Filament Theory](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-2-sliding-filament-theory.md)
  - [6.3.3 Contraction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-3-contraction.md)
  - [6.3.4 Slow & Fast Twitch Fibres](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-4-slow-and-fast-twitch-fibres.md)
  - [6.3.5 End of Topic Test - Muscles](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-5-end-of-topic-test-muscles.md)
  - [6.3.6 A-A* (AO3/4) - Muscle Contraction](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-3-6-a-a-ao34-muscle-contraction.md)
- 6.4 Homeostasis
  - [6.4.1 Overview of Homeostasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-1-overview-of-homeostasis.md)
  - [6.4.2 Blood Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-2-blood-glucose-concentration.md)
  - [6.4.3 Controlling Blood Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-3-controlling-blood-glucose-concentration.md)
  - [6.4.4 End of Topic Test - Blood Glucose](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-4-end-of-topic-test-blood-glucose.md)
  - [6.4.5 Primary & Secondary Messengers](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-5-primary-and-secondary-messengers.md)
  - [6.4.6 Diabetes Mellitus](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-6-diabetes-mellitus.md)
  - [6.4.7 Measuring Glucose Concentration](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-7-measuring-glucose-concentration.md)
  - [6.4.8 Osmoregulation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-8-osmoregulation.md)
  - [6.4.9 Controlling Blood Water Potential](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-9-controlling-blood-water-potential.md)
  - [6.4.10 ADH](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-10-adh.md)
  - [6.4.11 End of Topic Test - Diabetes & Osmoregulation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-11-end-of-topic-test-diabetes-and-osmoregulation.md)
  - [6.4.12 A-A* (AO3/4) - Homeostasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-12-a-a-ao34-homeostasis.md)
  - [6.4.13 Diagnostic Misconceptions - Effect of ADH](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/6-4-13-diagnostic-misconceptions-effect-of-adh.md)

### 7 Genetics & Ecosystems (A2 only)
- 7.1 Genetics
  - [7.1.1 Key Terms in Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-1-key-terms-in-genetics.md)
  - [7.1.2 Inheritance](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-2-inheritance.md)
  - [7.1.3 Linkage](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-3-linkage.md)
  - [7.1.4 Multiple Alleles & Epistasis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-4-multiple-alleles-and-epistasis.md)
  - [7.1.5 Chi-Squared Test](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-5-chi-squared-test.md)
  - [7.1.6 End of Topic Test - Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-6-end-of-topic-test-genetics.md)
  - [7.1.7 A-A* (AO3/4) - Genetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-7-a-a-ao34-genetics.md)
  - [7.1.8 Diagnostic Misconceptions - Dihybrid Inheritance](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-8-diagnostic-misconceptions-dihybrid-inheritance.md)
  - [7.1.9 Diagnostic Misconceptions - Sex Linkage](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-1-9-diagnostic-misconceptions-sex-linkage.md)
- 7.2 Populations
  - [7.2.1 Populations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-2-1-populations.md)
  - [7.2.2 Hardy-Weinberg Principle](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-2-2-hardy-weinberg-principle.md)
- 7.3 Evolution
  - [7.3.1 Variation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-1-variation.md)
  - [7.3.2 Natural Selection & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-2-natural-selection-and-evolution.md)
  - [7.3.3 End of Topic Test - Populations & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-3-end-of-topic-test-populations-and-evolution.md)
  - [7.3.4 Types of Selection](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-4-types-of-selection.md)
  - [7.3.5 Types of Selection Summary](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-5-types-of-selection-summary.md)
  - [7.3.6 Overview of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-6-overview-of-speciation.md)
  - [7.3.7 Causes of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-7-causes-of-speciation.md)
  - [7.3.8 Diversity](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-8-diversity.md)
  - [7.3.9 End of Topic Test - Selection & Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-9-end-of-topic-test-selection-and-speciation.md)
  - [7.3.10 A-A* (AO3/4) - Populations & Evolution](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-10-a-a-ao34-populations-and-evolution.md)
  - [7.3.11 Diagnostic Misconceptions - Types of Speciation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-3-11-diagnostic-misconceptions-types-of-speciation.md)
- 7.4 Populations in Ecosystems
  - [7.4.1 Overview of Ecosystems](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-1-overview-of-ecosystems.md)
  - [7.4.2 Niche](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-2-niche.md)
  - [7.4.3 Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-3-population-size.md)
  - [7.4.4 Investigating Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-4-investigating-population-size.md)
  - [7.4.5 End of Topic Test - Ecosystems & Population Size](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-5-end-of-topic-test-ecosystems-and-population-size.md)
  - [7.4.6 Succession](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-6-succession.md)
  - [7.4.7 Conservation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-7-conservation.md)
  - [7.4.8 End of Topic Test - Succession & Conservation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-8-end-of-topic-test-succession-and-conservation.md)
  - [7.4.9 A-A* (AO3/4) - Ecosystems](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/7-4-9-a-a-ao34-ecosystems.md)

### 8 The Control of Gene Expression (A2 only)
- 8.1 Mutation
  - [8.1.1 Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-1-mutations.md)
  - [8.1.2 Effects of Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-2-effects-of-mutations.md)
  - [8.1.3 Causes of Mutations](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-3-causes-of-mutations.md)
  - [8.1.4 Diagnostic Misconceptions - Gene Expression](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-1-4-diagnostic-misconceptions-gene-expression.md)
- 8.2 Gene Expression
  - [8.2.1 Stem Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-1-stem-cells.md)
  - [8.2.2 Stem Cells in Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-2-stem-cells-in-disease.md)
  - [8.2.3 End of Topic Test - Mutation & Gene Epression](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-3-end-of-topic-test-mutation-and-gene-epression.md)
  - [8.2.4 A-A* (AO3/4) - Mutation & Stem Cells](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-4-a-a-ao34-mutation-and-stem-cells.md)
  - [8.2.5 Regulating Transcription](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-5-regulating-transcription.md)
  - [8.2.6 Epigenetics](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-6-epigenetics.md)
  - [8.2.7 Epigenetics & Disease](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-7-epigenetics-and-disease.md)
  - [8.2.8 Regulating Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-8-regulating-translation.md)
  - [8.2.9 Experimental Data](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-9-experimental-data.md)
  - [8.2.10 End of Topic Test - Transcription & Translation](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-10-end-of-topic-test-transcription-and-translation.md)
  - [8.2.11 Tumours](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-11-tumours.md)
  - [8.2.12 Correlations & Causes](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-12-correlations-and-causes.md)
  - [8.2.13 Prevention & Treatment](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-13-prevention-and-treatment.md)
  - [8.2.14 End of Topic Test - Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-14-end-of-topic-test-cancer.md)
  - [8.2.15 A-A* (AO3/4) - Gene Expression & Cancer](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-2-15-a-a-ao34-gene-expression-and-cancer.md)
- 8.3 Genome Projects
  - [8.3.1 Using Genome Projects](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-3-1-using-genome-projects.md)
- 8.4 Gene Technology
  - [8.4.1 Recombinant DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-1-recombinant-dna.md)
  - [8.4.2 Producing Fragments](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-2-producing-fragments.md)
  - [8.4.3 Amplification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-3-amplification.md)
  - [8.4.4 End of Topic Test - Genome Project & Amplification](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-4-end-of-topic-test-genome-project-and-amplification.md)
  - [8.4.5 Using Recombinant DNA](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-5-using-recombinant-dna.md)
  - [8.4.6 Medical Diagnosis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-6-medical-diagnosis.md)
  - [8.4.7 Genetic Fingerprinting](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-7-genetic-fingerprinting.md)
  - [8.4.8 End of Topic Test - Gene Technologies](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-8-end-of-topic-test-gene-technologies.md)
  - [8.4.9 A-A* (AO3/4) - Gene Technology](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/8-4-9-a-a-ao34-gene-technology.md)

### 9 Mathematical Skills
- 9.1 Mathematical Skills
  - [9.1.1 Diagnostic Misconceptions - Converting Units](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-1-diagnostic-misconceptions-converting-units.md)
  - [9.1.2 Diagnostic Misconceptions - Correct Hypothesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-2-diagnostic-misconceptions-correct-hypothesis.md)
  - [9.1.3 Diagnostic Misconceptions - Interpret Hypothesis](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-3-diagnostic-misconceptions-interpret-hypothesis.md)
  - [9.1.4 Diagnostic Misconceptions - Calculate Uncertainty](https://senecalearning.com/en-gb/revision-notes/a-level/biology/aqa/9-1-4-diagnostic-misconceptions-calculate-uncertainty.md)